Regarding Xavier, it was pretty much explained that Moira's job was to "break him". You add that to the fact that dude rebooted himself two times already....at least Hickman explained why he's not the Xavier everyone knows. He didn't even bothered doing that on his Avengers run specially with Cap.
it makes sense why cap was an a$$hole in avengers. he became old in no time at all. so he went from vibrant young man to cranky old b*stard. and the illuminati was his bone that he couldnt let go of
i wonder what the lasting effects of moira fukking with his mind are gonna be