In Avengers: Infinity War's final few minutes, Thanos snapped his fingers while wielding the completed Infinity Gauntlet and wiped out trillions of lives. In the scene which followed, we saw the Mad Titan in a dreamlike world where he confessed to a younger version of Gamora - who he murdered to get the Soul Stone - that he had enacted his horrible plan but was that a dream or something else entirely?
Well, Joe Russo has confirmed that it was the Soul Stone they were having that conversation in, something which may confirm Gamora's soul has been trapped in there and can still be recovered.
"It is [in the soul stone], it’s an orange world that they’re in. Because he’s in the Hero’s Journey in the movie, we did point that out that there’s a correlating journey in the film between Thor and Thanos. Certain characters make very human choices in the movie that are very tragic that shift the direction of the storytelling. Quill makes that choice on Titan when he punches Thanos in the face. Thor makes that choice when he plunges the axe into Thanos’ chest because he wants to tell him that he got him, that this is payback. If he had not made that decision, had he gone for the kill, they wouldn’t be in this situation. For Thanos at the end of the movie, this is part of his Hero’s Journey, we once again put him face to face with the only thing that he cared about, where he has to own up to the emotional cost of what he’s done in the movie."