On a quick note about settings, as Grand Theft Auto V doesn't have pre-defined settings tiers, I want to quickly note what settings we're using. For "Very High" quality we have all of the primary graphics settings turned up to their highest setting, with the exception of grass, which is at its own very high setting. Meanwhile 4x MSAA is enabled for direct views and reflections. This setting also involves turning on some of the advanced redering features - the game's long shadows, high resolution shadows, and high definition flight streaming - but it not increasing the view distance any further.
Otherwise for "High" quality we take the same basic settings but turn off all MSAA, which significantly reduces the GPU rendering and VRAM requirements.