After working at
Sidley Austin LLP, Vance
moved to San Francisco to work in the tech industry as a venture capitalist.[21] He served as a principal at Peter Thiel's firm, Mithril Capital, between 2016 and 2017.[22][23]
In 2016,
Harper published Vance's book,
Hillbilly Elegy: A Memoir of a Family and Culture in Crisis. It was on
The New York Times Best Seller list in
2016 and
2017.
In December 2016, Vance indicated that he planned to move to Ohio to start a nonprofit, potentially run for office,[27] and work on combating drug addiction in the Rust Belt.[2]
In 2019, Vance co-founded
Narya Capital in Cincinnati with
financial backing from Thiel, Eric Schmidt, and Marc Andreessen.[31] In 2020, he raised $93 million for the firm.
[32] With Thiel and former Trump adviser Darren Blanton, Vance has invested in Rumble, a Canadian
online video platform popular with the political right.
[33][34]
In early 2018, Vance considered running for
U.S. Senate against
Sherrod Brown,
[35] but decided not to.
[36] In March 2021, Peter Thiel gave $10 million to Protect Ohio Values, a super PAC created in February to support a potential Vance candidacy;[37][38][39] Robert Mercer also gave an undisclosed amount.[37] In April, Vance expressed interest in running for the Senate seat being vacated by Republican
Rob Portman.
[40] In May, he launched an exploratory committee.
[41]
In July 2021, Vance officially entered the race;
[42] it was his first campaign for public office.
[43] On May 3, 2022, he won the Republican primary with 32% of the vote,[44] defeating multiple candidates, including
Josh Mandel (23%) and
Matt Dolan (22%).
[45] In the general election on November 8, Vance defeated
Democratic nominee
Tim Ryan with 53% of the vote to Ryan's 47%.
[46]
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