COVID-19 Pandemic (Coronavirus)

sportscribe

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Rwanda is not getting enough attention on the measures it's taking to stop the spread of the virus and ease the burden on its citizens. It's not all about excel spreadsheets brehs.











They are also doing a great job in tracking new cases, in particular those coming from outside of Rwanda. Might have to take a trip to Kigali when this is all over. :patrice:
 

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Sorry, conspiracy theorists. Study concludes COVID-19 'is not a laboratory construct'



Sorry, conspiracy theorists. Study concludes COVID-19 'is not a laboratory construct'
Some have suggested the virus is actually an engineered biological attack.


By
Kate Holland

March 27, 2020, 5:00 AM
5 min read

Coronavirus explainedEarly cases of COVID-19 are believed to be linked to a live-animal market in Wuhan, China.
Conspiracy theories claiming COVID-19 was engineered in a lab as part of a biological attack on the United States have been gaining traction online in recent weeks, but a new study on the origins of the virus has concluded that the pandemic-causing strain developed naturally.

An analysis of the evidence, according to the findings first published in the scientific journal Nature Medicine, shows that the novel coronavirus "is not a laboratory construct or a purposefully manipulated virus," with the researchers concluding "we do not believe that any type of laboratory-based scenario is plausible."


"There’s a lot of speculation and conspiracy theories that went to a pretty high level," Dr. Robert Garry, a professor at the Tulane University School of Medicine and one of the authors of the study, told ABC News, "so we felt it was important to get a team together to examine evidence of this new coronavirus to determine what we could about the origin."

Tune into ABC at 1 p.m. ET and ABC News Live at 4 p.m. ET every weekday for special coverage of the novel coronavirus with the full ABC News team, including the latest news, context and analysis.


Dr. Francis Collins, the director of the National Institutes of Health, supported the study’s findings, writing on his blog, "This study leaves little room to refute a natural origin for COVID-19."

Researchers concluded that the novel coronavirus is not a human creation because it does not share any "previously used virus backbone." It likely arose, the study said, from a recombination of a virus found in bats and another virus, possibly originating from pangolins, otherwise known as scaly anteaters.


MORE: Coronavirus live updates: US now leads world with over 82,000 cases

COVID-19 is 96% identical to a coronavirus found in bats, researchers said, but with a certain variation that could explain what has made it so infectious.

"We know from the study of other coronaviruses that they’re able to acquire this [variation] and they can then become more pathogenic," Garry told ABC News. "This is a good explanation as to why this virus is so transmittable and has caused this pandemic."


coronavirus-gty-jt-_hpMain_16x9_992.jpg

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This handout illustration image taken with a scanning electron microscope shows SARS-CoV-2 (yellow)also known as 2019-nCoV, the virus that causes COVID-19isolated emerging from the surface of cells (blue/pink) cultured in the lab.
This handout illustration image taken with a scanning electron microscope shows SARS-CoV-2 (yellow)also known as 2019-nCoV, the virus that causes COVID-19isolated emerging from the surface of cells (blue/pink) cultured in the lab.Handout/National Institutes of Health/AFP via GettY Images


The mutation in surface proteins, according to Garry, could have triggered the outbreak of the pandemic, but it’s also possible that a less severe version of the illness was circulating through the population for years, perhaps even decades, before escalating to this point.

"We don’t know if those mutations were picked up more recently or a long time ago," Garry told ABC News. "It’s impossible to say if it actually was a mutation that triggered the pandemic, but either way, it would have been a naturally occurring process."

And while many believe the virus originated at a fish market in Wuhan, China, Garry said that is also a misconception.

"Our analyses, and others too, point to an earlier origin than that," Garry said. "There were definitely cases there, but that wasn’t the origin of the virus."








Genomic Study Points to Natural Origin of COVID-19
Genomic Study Points to Natural Origin of COVID-19

Posted on March 26th, 2020 by Dr. Francis Collins



Sscanning electron microscope image of SARS-CoV-2 (round blue objects) emerging from the surface of cells cultured in the lab.


]No matter where you go online these days, there’s bound to be discussion of coronavirus disease 2019 (COVID-19). Some folks are even making outrageous claims that the new coronavirus causing the pandemic was engineered in a lab and deliberately released to make people sick. A new study debunks such claims by providing scientific evidence that this novel coronavirus arose naturally.

The reassuring findings are the result of genomic analyses conducted by an international research team, partly supported by NIH. In their study in the journal Nature Medicine, Kristian Andersen, Scripps Research Institute, La Jolla, CA; Robert Garry, Tulane University School of Medicine, New Orleans; and their colleagues used sophisticated bioinformatic tools to compare publicly available genomic data from several coronaviruses, including the new one that causes COVID-19.

The researchers began by homing in on the parts of the coronavirus genomes that encode the spike proteins that give this family of viruses their distinctive crown-like appearance. (By the way, “corona” is Latin for “crown.”) All coronaviruses rely on spike proteins to infect other cells. But, over time, each coronavirus has fashioned these proteins a little differently, and the evolutionary clues about these modifications are spelled out in their genomes.

The genomic data of the new coronavirus responsible for COVID-19 show that its spike protein contains some unique adaptations. One of these adaptations provides special ability of this coronavirus to bind to a specific protein on human cells called angiotensin converting enzyme (ACE2). A related coronavirus that causes severe acute respiratory syndrome (SARS) in humans also seeks out ACE2.

Existing computer models predicted that the new coronavirus would not bind to ACE2 as well as the SARS virus. However, to their surprise, the researchers found that the spike protein of the new coronavirus actually bound far better than computer predictions, likely because of natural selection on ACE2 that enabled the virus to take advantage of a previously unidentified alternate binding site. Researchers said this provides strong evidence that that new virus was not the product of purposeful manipulation in a lab. In fact, any bioengineer trying to design a coronavirus that threatened human health probably would never have chosen this particular conformation for a spike protein.


The researchers went on to analyze genomic data related to the overall molecular structure, or backbone, of the new coronavirus. Their analysis showed that the backbone of the new coronavirus’s genome most closely resembles that of a bat coronavirus discovered after the COVID-19 pandemic began. However, the region that binds ACE2 resembles a novel virus found in pangolins, a strange-looking animal sometimes called a scaly anteater. This provides additional evidence that the coronavirus that causes COVID-19 almost certainly originated in nature. If the new coronavirus had been manufactured in a lab, scientists most likely would have used the backbones of coronaviruses already known to cause serious diseases in humans.

So, what is the natural origin of the novel coronavirus responsible for the COVID-19 pandemic? The researchers don’t yet have a precise answer. But they do offer two possible scenarios.

In the first scenario, as the new coronavirus evolved in its natural hosts, possibly bats or pangolins, its spike proteins mutated to bind to molecules similar in structure to the human ACE2 protein, thereby enabling it to infect human cells. This scenario seems to fit other recent outbreaks of coronavirus-caused disease in humans, such as SARS, which arose from cat-like civets; and Middle East respiratory syndrome (MERS), which arose from camels.

The second scenario is that the new coronavirus crossed from animals into humans before it became capable of causing human disease. Then, as a result of gradual evolutionary changes over years or perhaps decades, the virus eventually gained the ability to spread from human-to-human and cause serious, often life-threatening disease.


Either way, this study leaves little room to refute a natural origin for COVID-19. And that’s a good thing because it helps us keep focused on what really matters: observing good hygiene, practicing social distancing, and supporting the efforts of all the dedicated health-care professionals and researchers who are working so hard to address this major public health challenge.

Finally, next time you come across something about COVID-19 online that disturbs or puzzles you, I suggest going to FEMA’s new Coronavirus Rumor Control web site. It may not have all the answers to your questions, but it’s definitely a step in the right direction in helping to distinguish rumors from facts.

Reference:
[1] The proximal origin of SARS-CoV-2 . Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry RF. Nat Med, 17 March 2020. [Epub ahead of publication]


 

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Rwanda is not getting enough attention on the measures it's taking to stop the spread of the virus and ease the burden on its citizens. It's not all about excel spreadsheets brehs.










They are also doing a great job in tracking new cases, in particular those coming from outside of Rwanda. Might have to take a trip to Kigali when this is all over. :patrice:

:manny:


 

jackswstd

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Probably going to stop coming into this thread now

Try and consume positive only news
I go on Youtube, the shyt pops up, watch tv some commercial about a fast food joint being here to serve you during the crisis plays. It's inescapable, 24 hour news cycles and social media.
 

bnew

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If I was Chinese, and you told me I have an off-chance of catching some newly mutated virus from eating something from a particular market, I wouldn't take my chances. End up with airborne HIV or some shyt.

You would think the market with all the bad press would die off naturally.

bruh, people still smoke cigarettes even when they see the graphic warning labels on the packs they buy. none of this behavior is surprising to me cause some people are wired differently in terms of what they see as dangerous. it is what it is:yeshrug:but in this case though those same individuals put others at risk if they live with multiple people and still venture outside unnecessarily:francis:

21o1imb.jpg
 

focusloco

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What's the chances the country gets poppin after April 30th....can somebody with factual info let me know because I'm trying to manage my finances right now....I'm helping a couple family members out right now but I don't how much longer I have to do this
...I'm in Vegas maybe @Absolut can help me out ....you seem dialed in on our local situation
 

NatiboyB

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What's the chances the country gets poppin after April 30th....can somebody with factual info let me know because I'm trying to manage my finances right now....I'm helping a couple family members out right now but I don't how much longer I have to do this
...I'm in Vegas maybe @Absolut can help me out ....you seem dialed in on our local situation


Word of advice from people who I know whose information I trust to include my wife...The peak has not hit and it’s still working it’s way into the interior of the country and small towns...Small towns aren’t going to be equipped for this.

I highly doubt things are back to normal by that proposed date. But I do believe a new normalcy will start to begin...Mask/gloves, no mass formations, social distancing in stores...Some industries may shift or lose some aspects.

It’s cool to help your family but by that point they will have to adapt you know what I mean...But continue to do what you are doing but start preparing them to find alternative means of getting money if they are able to...If not you may just be taking care of them long term.
 
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