COVID-19 Pandemic (Coronavirus)

Theo Penn

on that Earl Stevens wine
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Folks on MSNBC were trying to say that this is a lot different than the strain used for the vaccine :francis:



Dr. John Bell of Oxford University said Sunday the variant identified in South Africa was worrisome in this regard, however.

"They both have multiple, different mutations in them, so they're not a single mutation," he told Times Radio. "And the mutations associated with the South African form are really pretty substantial changes in the structure of the (virus' spike) protein."
 

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The virus could (can) mutate more in immunocompromised people, where the virus remains active in them for a long period of time before they pass it on to someone else.

U.K. variant puts spotlight on immunocompromised patients’ role in the COVID-19 pandemic

"In June, Ravindra Gupta, a virologist at the University of Cambridge, heard about a cancer patient who had come into a local hospital the month before with COVID-19 and was still shedding virus."

"When Gupta studied genome sequences from the coronavirus that infected the patient, he discovered that SARS-CoV-2 had acquired several mutations that might have allowed it to elude the antibodies."

"That strain, which appears to spread faster than others, contains one of the mutations that Gupta found, and researchers believe B.1.1.7, too, may have originated in an immunocompromised patient who had a long-running infection. “It’s a perfectly logical and rational hypothesis,” says infectious disease scientist Jeremy Farrar, director of the Wellcome Trust."

"But the new variant, along with research by Gupta and others, has also drawn attention to the potential role in COVID-19 of people with weakened immune systems. If they provide the virus with an opportunity to evolve lineages that spread faster, are more pathogenic, or elude vaccines, these chronic infections are not just dangerous for the patients, but might have the potential to alter the course of the pandemic."

"So far, SARS-CoV-2 typically acquires only one to two mutations per month. And B.1.1.7 is back to this pace now, suggesting it doesn’t mutate faster normally than other lineages. That’s why scientists believe it may have gone through a lengthy bout of evolution in a chronically infected patient who then transmitted the virus late in their infection. “We know this is rare but it can happen,” says World Health Organization epidemiologist Maria Van Kerkhove. Stephen Goldstein, a virologist at the University of Utah, agrees. “It’s simply too many mutations to have accumulated under normal evolutionary circumstances. It suggests an extended period of within-host evolution,” he says."

U.K. variant puts spotlight on immunocompromised patients’ role in the COVID-19 pandemic
 

StretfordRed

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the esteemed Oxford University no less :wow: ...

itvfCpLm.png

high ranking politicians no less :wow: ...

decided not to post this image ...

:ehh:
it's always good to listen to scientists and to understand what they say ... :salute: it's a new year, of good cheer so I'll just leave it at "bookmarked".

the bill always comes due.
:hula:

:ehh:

it's deja vu all over again .. #coli-science dusting off their textbooks ... bracing for those L's ...

Lol I guarantee none of our politicians will take the risks to post on TheColi :lolbron:

As the Oxford vaccine doesn’t use mRNA it’ll be less variable to the mutations. That’s not what I’m arguing.

We already know it won’t stop you getting it, you still need to keep distance, but you weren’t exactly clear about what your “silver bullet” comment was about. The vaccine itself or the situations around it e.g. hands, space, face.
 

Red Shield

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The virus could (can) mutate more in immunocompromised people, where the virus remains active in them for a long period of time before they pass it on to someone else.

U.K. variant puts spotlight on immunocompromised patients’ role in the COVID-19 pandemic

"In June, Ravindra Gupta, a virologist at the University of Cambridge, heard about a cancer patient who had come into a local hospital the month before with COVID-19 and was still shedding virus."

"When Gupta studied genome sequences from the coronavirus that infected the patient, he discovered that SARS-CoV-2 had acquired several mutations that might have allowed it to elude the antibodies."

"That strain, which appears to spread faster than others, contains one of the mutations that Gupta found, and researchers believe B.1.1.7, too, may have originated in an immunocompromised patient who had a long-running infection. “It’s a perfectly logical and rational hypothesis,” says infectious disease scientist Jeremy Farrar, director of the Wellcome Trust."

"But the new variant, along with research by Gupta and others, has also drawn attention to the potential role in COVID-19 of people with weakened immune systems. If they provide the virus with an opportunity to evolve lineages that spread faster, are more pathogenic, or elude vaccines, these chronic infections are not just dangerous for the patients, but might have the potential to alter the course of the pandemic."

"So far, SARS-CoV-2 typically acquires only one to two mutations per month. And B.1.1.7 is back to this pace now, suggesting it doesn’t mutate faster normally than other lineages. That’s why scientists believe it may have gone through a lengthy bout of evolution in a chronically infected patient who then transmitted the virus late in their infection. “We know this is rare but it can happen,” says World Health Organization epidemiologist Maria Van Kerkhove. Stephen Goldstein, a virologist at the University of Utah, agrees. “It’s simply too many mutations to have accumulated under normal evolutionary circumstances. It suggests an extended period of within-host evolution,” he says."

U.K. variant puts spotlight on immunocompromised patients’ role in the COVID-19 pandemic


:stopitslime:

you KNOW that's not why his sayin to focus on Africa
 
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