Basically...
Her DEA boyfriend started helping her out by busting her competition (Armenians I think). Armenians then killed her DEA boyfriend. Armenians and the black dudes then both tried to stick her up for all her shyt. After a long round-about series of nonsense Nancy ended up broke, and working for the Black dudes. In order to free herself from the black dudes she mad a deal with Mexicans. 2 seasons later her town was burned down by the Mexicans, and shes married to Mexican cartel boss/Mexican politician, and gets knocked up. Cartel boss had a c*nt friend/partner or something who wanted to kill Nancy because a Mexican politician with a gringo wife was a bad look. Nancy's son killed the c*nt. Then they went on the run for a season...a very long, ridiculous season during which she fukked Zach Morris and nothing else interesting happened.
Eventually she got caught, took the wrap for her son, went to jail for 3 years (i think). Last season was after her jail stint, she was sent to a half-way house in NYC where her family met up with her. All sorts of outlandish, and uninteresting shyt happened. She fukked Nicky Sobotka.
Ended up buying a house in CT with her annoying sister and family.
last scene of last season: