DEFENSE
Left defensive end (Arik Armstead): Had 19 tackles and two sacks as a rookie last year.
Nose tackle (Ian Williams): A force in the middle but might not be ready for opener after offseason ankle surgery.
Right defensive end (DeForest Buckner): Seventh overall pick in the draft had 67 defensive pressures in final college season.
Outside linebacker (Eli Harold): Will hold down the spot until Aaron Lynch completes four-game NFL suspension.
Outside linebacker (Ahmad Brooks): Has tied for the team lead in sacks each of the past three seasons.
Inside linebacker (NaVorro Bowman): Led the NFL in tackles one year after serious ACL injury.
Inside linebacker (Gerald Hodges): Made 39 tackles over final four games of 2015.
Cornerback (Tramaine Brock): Has to be looking over his shoulder after offseason trade rumors and the addition of three DBs in the draft.
Cornerback (Jimmie Ward): First-round pick in 2014 was in and out of the starting lineup in 2015.
Safety (Antoine Bethea): He was a 2014 Pro Bowl pick but missed nine games in '15 because of a torn pectoral muscle.
Safety (Eric Reid): Coming off a down year after making a combined seven interceptions in 2013 and 2014.
Punter (Bradley Pinion): Second-year punter tied for sixth with 31 punts inside the 20-yard line.
Kicker (Phil Dawson): The 41-year-old is third among active kickers with 457 career field goals.
Long-snapper (Kyle Nelson): Has not missed a game since taking over in 2014.
KR/PR (Bruce Ellington): Averaged 7.2 yards on punt returns and 25.6 on kickoff returns.
49ers could be without Ian Williams when season opens vs. Rams
Left defensive end (Arik Armstead): Had 19 tackles and two sacks as a rookie last year.
Nose tackle (Ian Williams): A force in the middle but might not be ready for opener after offseason ankle surgery.
Right defensive end (DeForest Buckner): Seventh overall pick in the draft had 67 defensive pressures in final college season.
Outside linebacker (Eli Harold): Will hold down the spot until Aaron Lynch completes four-game NFL suspension.
Outside linebacker (Ahmad Brooks): Has tied for the team lead in sacks each of the past three seasons.
Inside linebacker (NaVorro Bowman): Led the NFL in tackles one year after serious ACL injury.
Inside linebacker (Gerald Hodges): Made 39 tackles over final four games of 2015.
Cornerback (Tramaine Brock): Has to be looking over his shoulder after offseason trade rumors and the addition of three DBs in the draft.
Cornerback (Jimmie Ward): First-round pick in 2014 was in and out of the starting lineup in 2015.
Safety (Antoine Bethea): He was a 2014 Pro Bowl pick but missed nine games in '15 because of a torn pectoral muscle.
Safety (Eric Reid): Coming off a down year after making a combined seven interceptions in 2013 and 2014.
Punter (Bradley Pinion): Second-year punter tied for sixth with 31 punts inside the 20-yard line.
Kicker (Phil Dawson): The 41-year-old is third among active kickers with 457 career field goals.
Long-snapper (Kyle Nelson): Has not missed a game since taking over in 2014.
KR/PR (Bruce Ellington): Averaged 7.2 yards on punt returns and 25.6 on kickoff returns.
49ers could be without Ian Williams when season opens vs. Rams