There are several I complete at least once a year (OG SMB, SM3, SMW, and other NES/SNES/Genesis classics), but as for games I completed for the first time:
Brain Lord (SNES)
Silent Hill (PS1)
Ratchet and Clank PS3 games (ACiT, Tools of Destruction, Quest for Booty, Into the Nexus)
Zombies Ate My Neighbors/Ghoul Patrol (PS4)
Teenage Mutant Ninja Turtles Collection (PS5)
God of War: Ragnarok (PS5)
Horizon Forbidden West/Burning Shores
Hogwart's Legacy
FF7 Intermission DLC
Sackboay: A Big Adventure
Kena
FF7: Crisis Core
Zelda: A Link Between Worlds (3DS)
Mario Odyssey
Mario 3D World + Bowser's Fury
Halo: Combat Evolved (XBOX)
PSVR2:
Horizon: Call of the Mountain
Star Wars: Edge of the Galaxy
Moss: Books 1 and 2
Red Matter 2
Currently working through Walking Dead: Saints and Sinners part 1 (PSVR2) and FF16
Still have a lot in the backlog and I'm sure Spiderman 2 will jump in front of a lot of games