All the little systems and mechanics in One Piece Odyssey seem overwhelming at first, but the first few hours of the game do a good job of introducing things incrementally, so that everything fits together surprisingly well.
Tsuzuki stresses that One Piece Odyssey is meant to be approachable to players that don't typically play JRPGs, and my three hours with the game certainly give me hope it might live up to that dream. There's plenty of complexity for long-time turn-based fans, and plenty of references for One Piece fans. Nevertheless, the game's deliberate approach to its story and systems make it easy to pick up and play. It remains to be seen if its story and systems can remain interesting for dozens of hours, though.