Japan Approves First Human-Animal Embryo Experiments

[ColdSlither]

Japan aiming to be the first ones to make real life hentai.

 

[Secure Da Bag]

Japan aiming to be the first ones to make real life hentai.

Sextopus is

 

[Secure Da Bag]

Japan approves first human-animal embryo experiments

But getting human cells to grow in another species is not easy. Nakauchi and colleagues announced at the 2018 American Association for the Advancement of Science meeting in Austin, Texas, that they had put human iPS cells into sheep embryos that had been engineered not to produce a pancreas. But the hybrid embryos, grown for 28 days, contained very few human cells, and nothing resembling organs. This is probably because of the genetic distance between humans and sheep, says Nakauchi.

It doesn’t make sense to bring human–animal hybrid embryos to term using evolutionarily distant species such as pigs and sheep because the human cells will be eliminated from host embryos early on, says Jun Wu, who researches human–animal chimaeras at the University of Texas Southwestern Medical Center in Dallas. “Understanding the molecular basis and developing strategies to overcome this barrier will be necessary to move the field forward,” Wu says.

Nakauchi says the approval in Japan will allow him to attack this problem. He will be experimenting with iPS cells at subtly different stages, and trying some genetically modified iPS cells to try to determine what limits the growth of human cells in animal embryos.

The article seems to suggest that humans and rodents are evolutionarily closer than humans and sheep.

 

[DEAD7]

Sextopus is

 

[analog]

Japan approves first human-animal embryo experiments



The article seems to suggest that humans and rodents are evolutionarily closer than humans and sheep.

What good is a rodent sized kidney?

Start the human trials!

 

[Lord Beasley]

Since this is the goal, I support the effort to solve a problem. There's a reason why organ shortage is a problem in some countries while not in others

nah fukk this. creating animal life just to destroy it is not the answer. plus them mutants getting out can seriously fukk up ecosystems.

japan doesnt give a fukk about the environment either, mfs wanna know how to live longer im sure theres programs to create disease-resistant people

 

[Secure Da Bag]

creating animal life just to destroy it is not the answer.

That concerned me as well. Plus PETA is gonna be all over Berkeley soon enough.

plus them mutants getting out can seriously fukk up ecosystems.

That's the big problem.

 

[Isaiah Bradley]

nah fukk this. creating animal life just to destroy it is not the answer. plus them mutants getting out can seriously fukk up ecosystems.
japan doesnt give a fukk about the environment either, mfs wanna know how to live longer im sure theres programs to create disease-resistant people

It's absolutely the answer because it solves a human problem without disastrous results like animal extinction, like most health based solutions
I feel confident that no rodent with a human ear growing on its back finna escape the lab

Spoiler

without going down the rabbit's hole, the current version of humans suggest that whether it's animal farming, animal/human DNA splicing etc is all inevitable because space exploration and human desire to live longer will require speeding up/manipulating the evolution process

 

[Lord Beasley]

It's absolutely the answer because it solves a human problem without disastrous results like animal extinction, like most health based solutions
I feel confident that no rodent with a human ear growing on its back finna escape the lab

Spoiler

without going down the rabbit's hole, the current version of humans suggest that whether it's animal farming, animal/human DNA splicing etc is all inevitable because space exploration and human desire to live longer will require speeding up/manipulating the evolution process

i dont know how you feel confident about that when 1) PETA weirdos try to do this all the time and 2) we don't know what an ear rat mutant and a regular rat will produce in the wild + we know japan doesnt give a fukk about the environment. i'm 99% sure they dont follow all the rules when it comes to shyt with environmental consequences

we aint just talking ears man.

 

[Isaiah Bradley]

i dont know how you feel confident about that when 1) PETA weirdos try to do this all the time and 2) we don't know what an ear rat mutant and a regular rat will produce in the wild + we know japan doesnt give a fukk about the environment. i'm 99% sure they dont follow all the rules when it comes to shyt with environmental consequences

we aint just talking ears man.

PETA kills more animals they "rescue" because of finite resources and housing. So if they justify killing to solve over population, then these efforts to solve human problems should be allowed too
As long as the rodents aren't meant to roam the fields freely, then I don't see how they affect the eco system

Humans injecting animals/insects into new eco system via releasing unwanted pets and unknown stow away, caused problems not lab bait escaping

 

[Lord Beasley]

PETA kills more animals they "rescue" because of finite resources and housing. So if they justify killing to solve over population, then these efforts to solve human problems should be allowed too
As long as the rodents aren't meant to roam the fields freely, then I don't see how they affect the eco system

Humans injecting animals/insects into new eco system via releasing unwanted pets and unknown stow away, caused problems not lab bait escaping

thats a bigass problem, why you get boas and exotic pets ending up in ppls houses in suburbia. unless you're comparing a stray cat to a rat with human organs......

whatever gonna happen is gonna happen, don't make it right at all

 

[Isaiah Bradley]

thats a bigass problem, why you get boas and exotic pets ending up in ppls houses in suburbia. unless you're comparing a stray cat to a rat with human organs......
whatever gonna happen is gonna happen, don't make it right at all

but that's a problem due to careless and reckless humans outside of labs...unless it's been kept secret, I haven't heard lab animals escaping to cause eco problems

 

[Isaiah Bradley]

Scientists Propose Splicing Tardigrade DNA with Humans’

Human beings have long strived to push the boundaries of space exploration and habitation, from the race to the Moon, to the multi-country missions to Mars. But is the human body really the best suited for the next stage of space travel? Beyond the technological and aerospace advances, the largest challenge is also the greatest potential for a scientific revolution – the limitations of the human body’s response to long term and long-distance space travel.

Surprising, the being that is providing many answers to the secrets surrounding space travel might be found in the tiny tardigrade, the microscopic organism that has evolved to survive the most extreme natural circumstances, from the bottom of the ocean to space’s vacuum. Also called “water bears” or “moss piglets”, these organisms measure at .05mm long, but are found literally the world’s many environments. Their unique adaptation process includes being able to survive some of the most extreme heat temperatures and external pressures by shrinking and dehydrating to .001 percent of its original size.

Tardigrades in this stage are called “tuns” in which the organism shuts down it’s metabolism to a near-zero point or cryptobiosis, including complete dehydration and lowered oxygen levels. When they land in a habitable environment, tardigrades are able to rehydrate back to their normal state and size. Research has shown that this evolutionary flexibility carries ramifications beyond environmental hardiness to the actual lifespan of the microorganism. For example, the average lifespan for a tardigrade is 2.5 years; however, scientists have discovered ones in the Antarctic that may be as old as 30 years!

In contrast, the average lifespan of a human is said to be 79 years old, but the variables associated with this age expectancy can range from inherited genetics, economic status, education, geography, and more. Unlike the tardigrade, humans often have to rely on external factors against environmental extremes, both on earth and in space.

In addition to this being one of the most interesting scientific adaptations, could it be that the tardigrade’s biological flexibility could have implications for human space travel?


From Twins to Tardigrades: Will Genetic Engineering on Humans Prove Effective?
One of the biggest concerns of space travel is deep-space radiation exposure, especially as we push farther and farther into space. In 2015, NASA studied the genetic impact of deep and long term space on identical twin astronauts Mark and Scott Kelly in which one twin (Scott) traveled to space for a year, while the other twin (Mark) stayed on Earth. The difference was striking – Scott Kelly experienced severe physical stress including swelling and immune system overdrive, as well as marked differences in his telomeres, which lengthened in unusual ways, in contrast to his earth-bound twin brother.

The conclusions of this are helping drive the energy behind the exploration of the hybridization of humans and tardigrades capable of withstanding the physical rigors and radiation levels of space travel, specifically in the push to colonize Mars. If this sounds like the plotline out of a futuristic science fiction fantasy, this idea is perhaps closer than we may think.

Genetic engineering is nothing new and until 2012, it was a time and labor-intensive, messy process. But in 2012, a revolutionary new approach to genetic engineering was introduced – CRISPR, or Clustered Regularly Interspaced Palindromic Repeats which changed how we discover, map and manipulate genes. The recent CRISPR research is already being utilized to correct genetic mutations in embryos. Could the same cut and paste software approach that CRISPR employs be used to create a superhuman/tardigrade space species?

Scientists have studied tardigrade DNA to try to uncover the secret behind this almost indestructible organism. The research has been able to closely identify certain proteins emitted when exposed to adverse conditions, such as extreme heat and ice. Other proteins protect against damaging radiation exposure. The impact of this research is beginning to be looked at for biotechnology and medical applications, as well as readiness for deep and extended space travel and habitation.

Life on Mars; More Than Square Footage
As Mars colonization creeps closer to becoming a reality, NASA is beginning to look at what physical requirements will be needed for human habitation on the red planet Based on prototypes, the habitats would need to be self-sustaining, impeccably sealed, and with plenty of legroom. Researchers turned to the extended space travel in the International Space Stations for guidance, particularly when it comes to the need for extra square footage.

In contrast, tardigrades require little, or no, external intervention with the likelihood they could easily survive the extreme conditions on planet Mars. In 2007, a number of dehydrated specimens were released into the vacuum of space, with a surprising number not only surviving but being able to return to normal size and reproduce.

What does this all mean for humans and our seemingly unquenchable thirst for space travel? Will we allow genetic engineers to splice a human’s DNA with a tardigrade, in order to achieve conquering the ultimate frontier? Or will we accept our human limitations and look to apply the tardigrade’s reputation as the toughest being toward other scientific fields such as agriculture or health?

The danger in taking genetics into our own hands is that the end result may be in creating a species that is unable to live well in either environment, earth or space. Time will be the final decider as to whether the risk is worth what may be discovered.

Could We Splice Human DNA with Tardigrades' to Survive Space? | Gaia

Spoiler

without going down the rabbit's hole, the current version of humans suggest that whether it's animal farming, animal/human DNA splicing etc is all inevitable because space exploration and human desire to live longer will require speeding up/manipulating the evolution process

 

[DrBanneker]

It's absolutely the answer because it solves a human problem without disastrous results like animal extinction, like most health based solutions
I feel confident that no rodent with a human ear growing on its back finna escape the lab

Spoiler

without going down the rabbit's hole, the current version of humans suggest that whether it's animal farming, animal/human DNA splicing etc is all inevitable because space exploration and human desire to live longer will require speeding up/manipulating the evolution process

I am basically fine with medical genetics--growing organs, fixing disease/disability mutations etc. But of course people are going to want the custom designer baby, When you get to traits with many genes involved, it is hardly so simple though. But people want simple answers and solutions so it will probably get out of control.

 

[Isaiah Bradley]

I am basically fine with medical genetics--growing organs, fixing disease/disability mutations etc. But of course people are going to want the custom designer baby, When you get to traits with many genes involved, it is hardly so simple though. But people want simple answers and solutions so it will probably get out of control.

agree. More freedom offered, more laws needed
Just like they were explicit in banning abortion in certain states, by not just outlawing the practice but also threatening prison time for doctors and also the social pressures on women seeking it....some of these tactics can be used to stop custom designer babies