Beat the game on Institute, Railroad and Brotherhood variations
I beat it on the Institutes side
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but as soon as I became hostile with the brotherhood it turned out there was some buggy Brotherhood Lancer Initiate in Sanctuary that couldn't be targeted in VATS nor did it take any damage whatsoever
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she just ignored the whole fukking town throwing everything they got at her, didn't fight back either.
So now my whole settlement wasn't producing a thing because it was constantly under attack, I couldn't use my workbenches or fast travel away because 'enemies are nearby'
So I rushed the last main quests and started over with a different character build
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got myself an auto-shottie with explosive bullets of a legendary super mutant skirmisher
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build my main base at Red Rocket Truckstop to hopefully prevent some shyt like the above happening again