Beat the game on Institute, Railroad and Brotherhood variations
I beat it on the Institutes side
but as soon as I became hostile with the brotherhood it turned out there was some buggy Brotherhood Lancer Initiate in Sanctuary that couldn't be targeted in VATS nor did it take any damage whatsoever
she just ignored the whole fukking town throwing everything they got at her, didn't fight back either.
So now my whole settlement wasn't producing a thing because it was constantly under attack, I couldn't use my workbenches or fast travel away because 'enemies are nearby'
So I rushed the last main quests and started over with a different character build
got myself an auto-shottie with explosive bullets of a legendary super mutant skirmisher
build my main base at Red Rocket Truckstop to hopefully prevent some shyt like the above happening again