Coronavirus Thread: Worldwide Pandemic

jj23

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Breakthrough close on coronavirus antibody therapy: reports
Scientists say injection of cloned antibodies could help treat people already infected, while vaccine development continues

Press Association
Published:05:51 Sun 7 June 2020

Scientists working on coronavirus treatments may be close to a breakthrough on an antibody treatment that could save the lives of people who become infected, it has been reported.

An injection of cloned antibodies that counteract Covid-19 could prove significant for those in the early stages of infection, according to the British-Swedish pharmaceutical company AstraZeneca.

AstraZeneca’s chief executive Pascal Soriot told the newspaper that the treatment being developed is “a combination of two antibodies” in an injected dose “because by having both you reduce the chance of resistance developing to one antibody”.

Antibody therapy is more expensive than vaccine production, with Soriot saying the former would be prioritised for the elderly and vulnerable “who may not be able to develop a good response to a vaccine”.

On Thursday, AstraZeneca signed a deal with the Coalition for Epidemic Preparedness Innovations (Cepi) to help manufacture 300million globally accessible doses of the coronavirus vaccine candidate being developed by the Jenner Institute at the University of Oxford.

AstraZeneca has already started to manufacture the Oxford University Covid-19 vaccine to ensure that if it does pass human trials, it can be made available in the autumn. Trials of the potential vaccine have started in Brazil, a new epicentre of the pandemic, to ensure the study can be properly tested as transmission rates fall in the UK. The Jenner Institute and the Oxford Vaccine Group began development on a vaccine in January, using a virus taken from chimpanzees.

One member of Cepi is the Serum Institute of India, which the Sunday Telegraph reports is considering other “parallel” partnerships with AstraZeneca that may lead to the antibody treatment being funded as a stand-alone treatment.

Meanwhile UK-based vaccine manufacturer Seqirus announced it was working in partnership with parent company CSL, Cepi and the University of Queensland to help develop a candidate Covid-19 vaccine in Australia. Its manufacturing base in Liverpool is producing an adjuvant, an agent that improves the immune response to a vaccine.
 

jj23

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:francis: This seems to be a pattern across the world.

Care of the elderly seems like it may be the next human rights issue.

More than half of England’s coronavirus-related deaths will be people from care homes

Toll could hit 34,000 among country’s most vulnerable residents by end of June, estimates expert study

Care home residents are on course to make up more than half the deaths caused directly or indirectly by the coronavirus crisis in England, according to a new analysis.

The study warns that the death toll by the end of June from Covid-19 infections and other excess deaths is “likely to approach 59,000 across the entire English population, of which about 34,000 (57%) will have been care home residents”.

 

Yapdatfool

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if you don't want that protection in place for businesses, then how do you think it should be? just outta curiosity

i mean i hate to say it when you read about places like that packing plant, but how can we have a society where anyone can sue their job if they get coronavirus? it's not like you can even technically prove where you got it. it's just not gonna work :yeshrug:there's not gonna be workers on tape getting the virus. i don't know how you would prove that in court

Suing and winning are two different things and businesses take disputes to arbitration where they win damn near 100% of the time anyways.
The real slippery slope is the coverage they don't have to provide workers or customers. IMO this can give businesses and other entities the ability to not put forth a best effort to protect anybody not ONLY from covid but anything else that can result in harm or death.
But they have major protections anyway so it will be interesting to read the verbiage of the bill when it gets drafted up.
 

jj23

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Facinating read, trying to sort through why some places are harder hit by covid-19 than others

Are we underestimating how many people are resistant to Covid-19?

One thing seems clear: there are many reasons why one population is more protected than another. Theoretical epidemiologist Sunetra Gupta of the University of Oxford thinks that a key one is immunity that was built up prior to this pandemic. “It’s been my hunch for a very long time that there is a lot of cross-protection from severe disease and death conferred by other circulating, related bugs,” she says. Though that cross-protection may not protect a person from infection in the first place, it could ensure they only experience relatively mild symptoms.

In a paper published in Cell on 14 May, researchers at the La Jolla Institute for Immunology in California reported that T cells in blood drawn from people between 2015 and 2018 recognised and reacted to fragments of the Sars-CoV-2 virus. “These people could not have possibly seen Sars-CoV-2,” says one of the paper’s senior authors, Alessandro Sette. “The most reasonable hypothesis is that this reactivity is really cross-reactivity with the cousins of Sars-CoV-2 – the common cold coronaviruses which circulate very broadly and generally give rather mild disease.”

:ohhh:
 

88m3

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The Brazilian government has stopped sharing data showing the total number of people who have died from the novel coronavirus, a move that comes after South America's largest country saw its coronavirus death toll become the third-highest in the world.

Brazilian officials have stopped publishing data on total coronavirus fatalities in South America’s largest country after official numbers showed the third-highest death toll in the world.

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Brazil stops publishing coronavirus death total
Brazilian officials have stopped publishing data on total coronavirus fatalities in South America’s largest country after official numbers showed the third-highest death toll in the world.

demons
 

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