Probably suicide...pretty crazy some very smart people who do very well in school lose their purpose when they enter the next chapter of their lives. Work and the outside world hits you like a brick wall because there are no rules to play around...meaning go to class, do homework, study and get rewarded with a grade. The real world is grimey and doesn't always recognize hard work and dedication.
That's why i always teach the youngins to be good all around and find a medium not overdo things. It's nice to stay locked in your room and study to get that A, but being social, outgoing, and getting yourself in sticky situations is just as important to learn.