Damon Lindelof: "I'd say that the short answer is: That's his programming. In the scene preceding him doing that, he is talking to Weyland (although we don't know it at the time) and he's telling Weyland that this is a bust. That they haven't found anything on this mission other than the stuff in the vials. And Weyland presumably says to him, "Well, what's in the vials?" And David would say, "I'm not entirely sure, we'll have to run some experiments." And Weyland would say, "What would happen if you put it in inside a person?" And David would say, "I don't know, I'll go find out." He doesn't know that he's poisoning Holloway, he asks Holloway, "What would you be willing to do to get the answers to your questions?" Holloway says, "Anything and everything." And that basically overrides whatever ethical programming David is mandated by, [allowing him] to spike his drink."
if you take the point of view that blah blah blah blah blah"
