I don't know if my career took off, but like a lot of folks in here I have a degree in MIS, and I was working in IT. Always thought that's what I'd want to do until I took classes on crystal reports 5-6 years ago and since I worked in health care already, I was able to use that skill to pull data from their various systems and produce meaningful reports from the data they already had.
From that moment forward, I never wanted to work IT again and worked in healthcare informatics ever since. From that job, I got a job for a large hospital system that taught me a shytload in that area. Then I went to work for that healthcare software vendor. Each job change increased my pay 10k or more. Then that last job let me go in April. And in late may, I was offered another informatics job for a hospital system in Dallas. I'm changing locations, but the job is exactly what I want to do.
I don't have certs nor do I have student loan debt. But I do have lots of healthcare experience and hospitals love hiring analyst that have been in there industry.