Miguel Cabrera is 13 hits away from 3,000 for his career. He already has 502 career home runs.
It looks like we won't see another player reach 3,000 hits for a long time. Robinson Cano is 376 hits away but he's 39 years old.
Realistically, you're looking at Jose Altuve (1,777 hits, 31 years old) and Freddie Freeman (1,704 hits, 32 years old). Obviously there is Mike Trout and Manny Machado but they're not even halfway there.
The 500 home run club will be quiet for a while. Giancarlo Stanton has 347 and Mike Trout has 310. Stanton could get there quickly but he's got to remain healthy and put together some monster seasons. I think the older he gets, it will be difficult because he's not really a good enough hitter to stick around for a long time. If he starts hitting .240 with 20 home runs, I don't know that he will have enough regular season at bats to get there in time. He could be relegated to part time play. Trout is more of a compiler and has a better chance. He doesn't have the raw power to hit 55-60 like Stanton does. But he could Hank Aaron his way well past 500...just banking 35-45 every year.
As far as 300 wins, I think that ship has sailed. No one will ever get 300 wins again. Verlander is the active leader with 226. After him you've got Greinke with 219. Everyone else is under 200. Could Kershaw get to 300? Well he's got 185 wins and he will turn 34 years old next month. If he goes for another 5-6 years, he'd have to average out 19 wins a year. Best case scenario for him is if he pitches until his mid-40s the way Clemens did. It's hard to see that happening. Unless he gets on the juice.
I think an interesting question would be = Could Max Scherzer get to 4,000 strikeouts? Currently he sits at 3,020. He turns 38 in July. Is it likely? Not at all. Is it possible? Well...I'd say there's a better chance of this happening than anyone getting 300 wins again. Last season Scherzer struck out 236 batters. If he could stick around a few more years...with the way hitters are whiffing these days, maybe. If he does get to 4,000 he would join Nolan Ryan, Randy Johnson, Roger Clemens, and Steve Carlton as the only men in history to do it.
And finally, here's a question.
Is Zack Greinke a Hall of Fame pitcher in your mind?
As of this writing: 219-132 record. 2,809 strikeouts. 1 Cy Young Award (and 4 top 10 finishes). 68.0 WAR value (less than Kevin Brown, who is not in the HOF -- but more than John Smotlz, who IS in the HOF).
If I'm being fair, it shouldn't matter what Brown or Smoltz did since Greinke didn't compete in their era, but I just wanted to give some context historically.
In reality he should be looked at alongside Scherzer, Verlander, Lincecum, King Felix and possibly Kershaw. Because those were the elite guys from 2004 to the current time.
I think Greinke probably does belong. But I will say he doesn't seem to stand out much in terms of popularity or narrative. That could just be a personality or perspective thing. There's probably some bias there. But we all know how these things shake out.