I don't have kids. But it's so annoying to listen to people without kids act like people with children are miserable. Because that's really all Seth Rogen is saying here.
"I have time to do all the things I want to do and all the things I need to do" = I smoke weed a lot. Like, A LOT. And not having kids allows me to smoke A LOT OF WEED. And bang my wife sometimes. And if I need to make a movie to fund my lifestyle of smoking a lot of weed, I can do that. Because I don't have kids. And the responsibility of having kids can limit parents' ability to do what they want to do.
That's REALLY what he's saying.
Which is fine.
But that's the subtext and it sounds a lot more goofy than the dressed up bullshyt he said in that video.
Edit - Because I got called out on it in a later post, I'll clarify that it's annoying to have to listen to his explanation for why he doesn't have kids.
But it's fine that he chose not to have kids, as a personal decision.