Chain gun with rocket launcher (chain gun is telemtry spike + something)...put as much damage as you can on chain gun with a elemental damage addon, rocket launcher doesnt really matter but I use clip and reload mostly once damage is maxed. Chain gun eats trough anything. Cuts down bigger mobs and with 110 clip you obliterate the ones who come in big packs. Rocket launcher's there for emergencies and cleanup u can trade that one out dependin on preference. But the thing with this game is that once you get a lot of +damage upgrades any gun can kill in a couple shots. What becomes important is size of the clip and rate of fire.
