The ad is misleading and attempts to paint a direct correlation to Bain closing the place where Joe Soptic worked and his wife's death.
The ad glosses over the timeline and some important facts though.
Soptic lost his job in 1999, his wife had her own insurance from her own job, Soptic got a job as a janitor after bing laid off, his wife worked at her own job until 2003 when she quit due to a rotator cuff injury, in 2006 she started feeling ill and after visiting a doctor found out she had stage 4 cancer and died not long after.
Also Romney was not running the day to day operations of Bain when the factory closed.