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Poitier

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"These results suggest that an APBA2 (OCA2) mutation conferring light skin arose BEFORE the spread of humans out of Africa" They said it not me.

And 50,000 years later means its not African :snoop:
 

Bawon Samedi

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I posted stuff several times. This is all current science there not going to out right say at the gate HEY EVERYBODY BLUE EYES AND BLONDE HAIR CAME FROM AFRICA!!. Their debunking the old ass 1970s thought that it came from Europe/Asia and that we some how genetical originated differently.


No I read all the studies you posted(out of context) and none of them HINT/INDICATE that the gene for pale skin and blonde hair was always carried by Africans. That's the argument.
 

Bawon Samedi

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Another study posted out of context.

Another study ...
Human skin color diversity is highest in sub-Saharan African populations.
Relethford JH.
Author information
  • Department of Anthropology, State University of New York College at Oneonta, 13820, USA.
Abstract
Previous studies of genetic and craniometric traits have found higher levels of within-population diversity in sub-Saharan Africa compared to other geographic regions. This study examines regional differences in within-population diversity of human skin color. Published data on skin reflectance were collected for 98 male samples from eight geographic regions: sub-Saharan Africa, North Africa, Europe, West Asia, Southwest Asia, South Asia, Australasia, and the New World. Regional differences in local within-population diversity were examined using two measures of variability: the sample variance and the sample coefficient of variation. For both measures, the average level of within-population diversity is higher in sub-Saharan Africa than in other geographic regions. This difference persists even after adjusting for a correlation between within-population diversity and distance from the equator. Though affected by natural selection, skin color variation shows the same pattern of higher African diversity as found with other traits.

This is a study I posted many times on here. All they say Africa has the highest skin variation, not that Africa has every single skin tone. And again nowhere does it state pale skin evolved in Africa.
 

Oceanicpuppy

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Yes BEFORE not 50,000 years AFTER :leostare:

:camby:

Meaning the mutation happened in Africa like i've been saying this whole time but you kept saying no no no..


No I read all the studies you posted(out of context) and none of them HINT/INDICATE that the gene for pale skin and blonde hair was always carried by Africans. That's the argument.
Yes do go back and read read them.
 

Bawon Samedi

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That's not what i'm arguing. It's the genes that originated in Africa, again stop thinking about superficial traits.

And again natural selection/selective mating is why it's not in an African environment. Darker skin proved to be benefcial that is why it's there.

Again none of your studies even state that. And for the last time LOOK UP SNP GENETIC EVENTS!:snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop:
 

Oceanicpuppy

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Nikka, they said it the conclusions of the studies. I've post them several times
Again none of your studies even state that. And for the last time LOOK UP SNP GENETIC EVENTS!:snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop:
Although ecological and environmental factors may be sufficient to explain the observed change in European skin pigmentation, these explanations are unlikely to hold for eye and hair color. The geographic distribution of iris and hair pigmentation variation does not conform as well to a latitudinal cline model, with much of the observed phenotypic variation restricted to Europe and closely related neighboring populations (51, 52). The blue iris phenotype characteristic of the HERC2 rs12913832 G allele, for example, is almost completely restricted to western Eurasia and some adjacent regions, its descendant populations, and populations containing European admixture (51, 52). It is possible that depigmented irises or the various human hair color morphs in Europeans are by-products of selection on skin pigmentation.

These results suggest that an APBA2 (OCA2) mutation conferring light skin arose BEFORE the spread of humans out of Africa" I explained this early in the post.


The TYRP gene family evolved by recurrent gene duplication from a common ancestral TYR early in evolution giving rise to TYRP1 and DCT [80]. In humans, mutations of TYRP1 causing OCA3 are frequently observed in South Africa [13]. Part of this phenotype is red bronze skin, ginger-red hair and blue irides.
In a surprising finding, it was recently reported that a nonsynonymous amino acid change, Arg93Cys, in the TYRP1 protein is a major determinant of the blonde hair phenotype.

They said this!



They debunked that it was not from the environment.
 
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Oceanicpuppy

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Again none of your studies even state that. And for the last time LOOK UP SNP GENETIC EVENTS!:snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop::snoop:
You've already said the gene SLC24A5 was not found in Africans
SLC24A5/SLC24A2 WAS found in Africans,

They already debunked that.





I've said many times you can have the genes but not phenotype

The association of HERC2 and SLC24A5 with eye color is also apparent in individuals who do not have blue or green eyes: In the subset of 592 Cape Verdeans whose T-index .0.15 (Figure 1, Figure 2), both loci remain highly significant (HERC2 rs12913832, P = 5.23610216; and SLC24A5 rs2470102, P = 1.12610210), indicating that variation at these loci affects different shades of brown eye color.

 

Bawon Samedi

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Here's the full study that you decided to leave out.
Direct evidence for positive selection of skin, hair, and eye pigmentation in Europeans during the last 5,000 years
http://www.pnas.org/content/111/13/4832.full


Although ecological and environmental factors may be sufficient to explain the observed change in European skin pigmentation, these explanations are unlikely to hold for eye and hair color. The geographic distribution of iris and hair pigmentation variation does not conform as well to a latitudinal cline model, with much of the observed phenotypic variation restricted to Europe and closely related neighboring populations (51, 52). The blue iris phenotype characteristic of the HERC2 rs12913832 G allele, for example, is almost completely restricted to western Eurasia and some adjacent regions, its descendant populations, and populations containing European admixture (51, 52). It is possible that depigmented irises or the various human hair color morphs in Europeans are by-products of selection on skin pigmentation.


They debunked that it was not from the environment.

No.:snoop: They're not agreeing with your theory that Africans always carried the pale skin, blonde hair and blue eyes genes. They don't even hint it. Yes the only thing that supports your argument is that they say European hair/eye is not due to environment. Neither I or anyone else on this thread concluded that it was due to that. Again nowhere does it state these genes evolved in Africa. But yet they do agree that pale is was due to environment (vitamin D) was a main factor in pale skin in Europe. Killing your claim that it was not solely due to environment... If environment doesn't play an effect on phenotype, then Africa wouldn't have the highest diversity of phenotypes in the world. And why don't you read what you post?:snoop:

The blue iris phenotype characteristic of the HERC2 rs12913832 G allele, for example, is almost completely restricted to western Eurasia and some adjacent regions, its descendant populations, and populations containing European admixture (51, 52). It is possible that depigmented irises or the various human hair color morphs in Europeans are by-products of selection on skin pigmentation.

Another source that kills your theory. This one is about blue eyes:


Summery
New research shows that people with blue eyes have a single, common ancestor. Scientists have tracked down a genetic mutation which took place 6,000-10,000 years ago and is the cause of the eye color of all blue-eyed humans alive on the planet today.

Whats this??? 6,000-10,000 years? Thats WAAAY after the OOA.:beli:

What is the genetic mutation

“Originally, we all had brown eyes”, said Professor Eiberg from the Department of Cellular and Molecular Medicine. “But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a “switch”, which literally “turned off” the ability to produce brown eyes”. The OCA2 gene codes for the so-called P protein, which is involved in the production of melanin, the pigment that gives colour to our hair, eyes and skin. The “switch”, which is located in the gene adjacent to OCA2 does not, however, turn off the gene entirely, but rather limits its action to reducing the production of melanin in the iris – effectively “diluting” brown eyes to blue. The switch’s effect on OCA2 is very specific therefore. If the OCA2 gene had been completely destroyed or turned off, human beings would be without melanin in their hair, eyes or skin colour – a condition known as albinism.

Limited genetic variation

Variation in the colour of the eyes from brown to green can all be explained by the amount of melanin in the iris, but blue-eyed individuals only have a small degree of variation in the amount of melanin in their eyes. “From this we can conclude that all blue-eyed individuals are linked to the same ancestor,” says Professor Eiberg. “They have all inherited the same switch at exactly the same spot in their DNA.” Brown-eyed individuals, by contrast, have considerable individual variation in the area of their DNA that controls melanin production.

Professor Eiberg and his team examined mitochondrial DNA and compared the eye colour of blue-eyed individuals in countries as diverse as Jordan, Denmark and Turkey. His findings are the latest in a decade of genetic research, which began in 1996, when Professor Eiberg first implicated the OCA2 gene as being responsible for eye colour.

Nature shuffles our genes

The mutation of brown eyes to blue represents neither a positive nor a negative mutation. It is one of several mutations such as hair colour, baldness, freckles and beauty spots, which neither increases nor reduces a human’s chance of survival. As Professor Eiberg says, “it simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”
Source:
http://www.sciencedaily.com/releases/2008/01/080130170343.htm

Again for the last flipping time save us the trouble and actually RESEARCH genetic mutation/SNP events.
 

Bawon Samedi

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And one can see that this character is clearly ignorant of genetic mutation. Even going as far to dismiss that the environment plays no role in genetic mutation/phenotype. If we want to get technical evolution and environment go hand and hand; when the environment suddenly changes or people/creatures move to new environment, the changed conditions are required for a species to survive. Now what happens is that individual member of a population with a different gene than the rest (via random mutation) might be more capable of survival in these changed conditions. Why the heck do you think species like whales who are mammals are now able to be marine type animals??? Because they wanted to? No. IIRC the whales ancestor was a land animal. Same thing with DNA mutation. The environment the plays many factors; ultraviolet radiation, vitamins, diet, climate, diseases,smoking,etc,etc.
 
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