In a vacuum I think Kyrie is a more skilled player with more overall potential at only 25 years old than Dame, but only by a negligible amount in the grand scheme of things. Dame has him beat handily in terms of health/longevity: the most games Kyrie's ever managed in a season is 75; Dame's never played LESS than 75 games in a season in his career. For that alone I'd take Dame if I'm trying to build a team with either as the #1 option. Both are not good on defense but I think Kyrie is even more of a sieve than Dame is, which doesn't help is case.