I remember like 6 months before his death, his fans were literally BEGGING him to get an assistant. Like literally begging him either in the comment section or the live stream. He would always reply "I don't need no assistant. I run a million dollar business by myself"
Also there were times when I would see a new video up of his main late night show, then I would see Instagram clips of stuff he would do in the afternoon. Like when does he have time to sleep?
Was it that hard to hire an assistant to be your sound check/mixer/IT guy? And maybe another one who schedules appointments for you?
Then you mix that with a bad diet