if it was my best friend yeah I would.
I had two friends come out as gay within like the past 2 months. Luckily I didn't really hang out with them much so it wasn't a problem. It certainly can make things weird because then you start questioning whether they like you or not.
after one of my friends recently came out as gay, I had posted a selfie on facebook and dude commented "you're one handsome son of a bytch"
now, if it were one of my straight friends that said that I'd take it as a compliment, but the fact that I know the dude is gay who said that makes things
so I guess it also depends on the person that is coming out as gay. Dude probably hoped that I was gay as well.