It won't hurt his ranking...
BUT
people will reeavulate him and open the door for putting other guys like Kobe over him. Because the eastern conference was crap - ESPECIALLY during LeBron's 2nd Cleveland stint. We literally had a 53-win Celtics team led by Isaiah Thomas go number 1 in the standings in 2017, for christ's sake. The reality is that take some of those Cavs teams he had and put them in the West... LeBron ain't going to 8 straight finals.
Kobe had to go through the west with Pau Gasol and Lamar Odom.
Hell, Curry won 73 games and made 2 straight Finals going through the west with his best teammates being Draymond Green and Klay Thompson - who both have serious flaws in their game that Curry covered up those years.
More importantly, Lebron in the west - missed playofffs, won with AD, then lost his first 1st round ever potentially with AD getting hurt... it's not a good look.
He'll be in the GOAT debate stil... but he will probably slide around. Basically, it'll be acceptable to put him top 5 or top 6 or so.