COVID-19 Pandemic (Coronavirus)

BK The Great

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They better find another cure because I ain’t taking no fukking boosters. I’m still double masked up too and for the time being.
 

Macallik86

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One theory that comes to mind is whether the Delta variant was widely prevalent when the initial +90% efficacy rates were announced. If not, then the vaccines didn't lose effectiveness as much as the competition increased.
 

threattonature

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So whoever has the booster, which one did you get? Apparently you can get whatever you want lol. I got my second dose of the Moderna vax in April and am due for my booster. Scheduled to get a Moderna booster tomorrow
I got the Moderna booster two weeks ago. My original Moderna was back in April.
 

Orbital-Fetus

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Belgium has one of the highest vaccination rates in the world. Record cases and majority of hospitalitizations are vaccinated :jbhmm:


viruses evolve.
they would have gotten even sicker without the vax.

if someone is injured in a car accident and wearing a seatbelt that does not mean that wearing a seatbelt is useless.

think like a child, brehs...
 

Actually6Foot3

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viruses evolve.
they would have gotten even sicker without the vax.

if someone is injured in a car accident and wearing a seatbelt that does not mean that wearing a seatbelt is useless.

think like a child, brehs...
goal post moving.

Goes entirely against the narrative of “only the unvaccinated are being hospitalized” y’all been running with :troll:
 

null

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One theory that comes to mind is whether the Delta variant was widely prevalent when the initial +90% efficacy rates were announced. If not, then the vaccines didn't lose effectiveness as much as the competition increased.

antibody levels fall over the period :ufdup:

Antibody titer[edit]
An antibody titer is a measurement of how much antibody an organism has produced that recognizes a particular epitope. It is conventionally expressed as the inverse of the greatest dilution level that still gives a positive result on some test. ELISA is a common means of determining antibody titers. For example, the indirect Coombs test detects the presence of anti-Rh antibodies in a pregnant woman's blood serum. A patient might be reported to have an "indirect Coombs titer" of 16. This means that the patient's serum gives a positive indirect Coombs test at any dilution down to 1/16 (1 part serum to 15 parts diluent). At greater dilutions the indirect Coombs test is negative. If a few weeks later the same patient had an indirect Coombs titer of 32 (1/32 dilution which is 1 part serum to 31 parts diluent), this would mean that she was making more anti-Rh antibody, since it took a greater dilution to abolish the positive test.

Many traditional serological tests such as hemagglutination or complement fixation employ this principle. Such tests can typically be read visually, which makes them fast, cost-effective, and able to be deployed in a wide variety of laboratory environments. The interpretation of any serological titer result is guided by reference values that are specific to the antigen or antibody in question, so a titer of 1:32 may be below the cut-off for one test but above for another.

Titer - Wikipedia
 

Macallik86

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antibody levels fall over the period :ufdup:

Antibody titer[edit]
An antibody titer is a measurement of how much antibody an organism has produced that recognizes a particular epitope. It is conventionally expressed as the inverse of the greatest dilution level that still gives a positive result on some test. ELISA is a common means of determining antibody titers. For example, the indirect Coombs test detects the presence of anti-Rh antibodies in a pregnant woman's blood serum. A patient might be reported to have an "indirect Coombs titer" of 16. This means that the patient's serum gives a positive indirect Coombs test at any dilution down to 1/16 (1 part serum to 15 parts diluent). At greater dilutions the indirect Coombs test is negative. If a few weeks later the same patient had an indirect Coombs titer of 32 (1/32 dilution which is 1 part serum to 31 parts diluent), this would mean that she was making more anti-Rh antibody, since it took a greater dilution to abolish the positive test.

Many traditional serological tests such as hemagglutination or complement fixation employ this principle. Such tests can typically be read visually, which makes them fast, cost-effective, and able to be deployed in a wide variety of laboratory environments. The interpretation of any serological titer result is guided by reference values that are specific to the antigen or antibody in question, so a titer of 1:32 may be below the cut-off for one test but above for another.

Titer - Wikipedia
Welp, since you forced me to do my Googles, this appears to be standard for vaccines out here. Here is a paper on the 2nd shot for Measles/Mumps/Rubella (referred to as 'MMR2' in the paper)
For the 602 children who had medium or high antibody levels before MMR2, titers increased significantly at 1 month but returned to pre-MMR2 levels by 6 months, at which point only 1.0% (6/583) had titers 4-fold higher than at baseline. Of these 602 children, 1 (0.2%) had a positive IgM response and 4 (0.7%) had an indeterminate response. Kindergarteners had significantly higher titers than middle schoolers both 1 month and 6 months after MMR2.

Of 2428 post-MMR2 specimens tested, 32 (1.32%) showed potential susceptibility (≤120 mIU/mL), but none was negative (<8 mIU/mL). Titers fell significantly over time for the study population overall and, by the final collection, 4.7% (18/382) of children were potentially susceptible, not significantly different from the pre-MMR2 proportion (3.1% [19/621), though none was negative.

Here is the main takeaway:
A rise in the proportion of persons with low antibody levels suggests an increase in potential susceptibility, but low titers are unlikely to represent the same risk of illness or viral transmission as absent antibodies.28,37-39 In our study, none of the children with low titers had positive or even indeterminate IgM responses to MMR2, in contrast to the majority of those with negative titers, suggesting that those with low titers may generate an anamnestic response to wild-type virus, consistent with previous studies.37-39 If ongoing viral transmission requires that a substantial portion of the population be antibody-negative, our data suggest that such a situation may be several decades away. .

Here is a screenshot of titer's reverting to (or below) the average starting point:
poa60088f2.png
Source: Persistence of Measles Antibodies After 2 Doses of Measles Vaccine in a Postelimination Environment
 

Orbital-Fetus

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goal post moving.

Goes entirely against the narrative of “only the unvaccinated are being hospitalized” y’all been running with :troll:

do whatever the fukk it is you wanna do or don't do.
me and every single person i know irl have been vaxxed and some have gotten boosters.
since being vaxed none of them has gotten covid. before the vax a bunch of my in laws got it.
luckily none of them were hospitalized. i'll be getting my booster soon, think i'm gonna go with
Moderna since my first two were Pfizer. I really want that elite Russian Sputnik vax.
 

null

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Welp, since you forced me to do my Googles, this appears to be standard for vaccines out here. Here is a paper on the 2nd shot for Measles/Mumps/Rubella (referred to as 'MMR2' in the paper)

Here is the main takeaway:

wut? give me a connected assertion breh.


or is it random points friday :ld:?
 
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