Mimi from The Drew Carey Show... If you ever watched this show... you know why.
older Ashley from The Fresh Prince, Hilary sometimes, for her Valley Girl airhead mannerisms and speech. especially the dude's she went after. that homo Trevor for one. the lightskin Aunt Viv, and all of Will's Aunts were annoying too.
Gina from Martin had some annoying scenes, mostly for her high pitched voice though. like nails on a chalkboard.
all the "white-washed" dude's Fancy dated on The Jamie Foxx Show, Jamie's homeboy Mouse, and Fancy's friend Sheila.
Jill from Home Improvement, and when Mark got older.
Lovita from The Steve Harvey Show, matter of fact damn near all the students on that show was annoying to me. Romeo, Lydia, Bullethead and Sophia.
Rachel from Friends, Ross' british wife Emily (hated this dumb c*nt), both Ross' first wife, Carol and her girlfriend Susan and Chandler's roommate Eddie after Joey moved out of his apartment during season 2. oh and that Asian bytch that Ross came back from China with. I forgot her name.
pretty much every one of the kids on Step By Step.
*edit*
just remembered Father Intiltola from The Sopranos, I wanted him to have something more with Carmela, just so Tony could find out and have him murked.