Kentucky is also questionable
NC is on there
but no Mississippi
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The most inbred state in the country is Kentucky.
This might come as a shock, especially if you’re from Kentucky. But
the state has a surprisingly high amount of consanguinity (inbreeding). Why is this? And why does it matter?
The reason is that people moved to the mountains where the cost of living is cheaper.
People with common ancestors in Appalachia and isolated communities are more likely to intermarry. This geographic and cultural isolation has led to an exceptionally high level of genetic isolation.
A prominent example is the Fugate Family. The Fugates of Kentucky, who have lived for centuries in Pike County in the Appalachian Mountains, is a family of people with an inherited disorder.
The most intriguing thing about the Fugates is their rare blue skin. They came into light because of their rare blue skin condition, which occurs when the related parents pass down recessive genes onto an offspring."
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Inbreeding is common, specifically, in the eastern part of Kentucky, and the region is plagued by the stereotype that every family is an inbred family. While the stereotype is not entirely true,
inbreeding rates are higher in eastern Kentucky than in any other part of the state. It is believed that this is partially because
people have moved to the mountains in eastern Kentucky for the low cost of living and the lifestyle. Still, there are typically no other families living in these locations. The families that move there either don’t have the money to leave or do not want to leave, and the growing children typically inbreed to save their family name.
One family from Kentucky known for generations of inbreeding is the Fugate family. The Fugate family was relatively isolated from the rest of society for nearly 200 years. Their inbreeding led to several medical problems and recessive genes being passed down through each child, such as one that gave some of the offspring blue skin. The blue skin gene is a recessive gene that only appears when both parents are carriers of the gene. The inbreeding caused the recessive gene to appear in both parents."