If the studios want a Creed sequel that will happen regardless of whether or not Coogler's involved. The fact that he's in talks period means he's open to the idea.Don't think he will be, read he's got another movie in the plans to make with Jordan and a Creed sequel is likely to be announced.
This will all depend on Marvel's pitch though. If he's allowed some freedom he'll probably take it. If Marvel is going to be too hands on then I can see him bouncing or if he feels it's too much pressure which is also a possibility.