They're even doing shyt like stealing avocados to make money. As well as extortion
In a world with no drugs or legalized drugs in the US, they would probably lose a lot of money. But they would not go extinct as they've been expanding their source of income beyond selling cocaine and heroin.
They make way less money from selling marijuana these days for obvious reasons, yet they're stronger than ever.
Right after the Great Recession, there was talk that it was cartel money that was bolstering the liquidity in the economy. The drug money was the only money that was flowing like before, and one of the few reasons some of the bigger banks didnt fold since they had laundered drug money in their reserves