OK now I have to add the last level of Astro Bot to this.Didn't cry but it was hard to watch Joel go out like that in the last of us. I literally put the controller down and said "no".
Arthur Morgan's death was tough too.
Dom's death in Gears of War....man , that was another one. Also when he finds his wife .
Who else?.....
Halo Reach - ending, The Walking Dead - Lee death, RDR - John Marston death, Jin vs Ryuzo in Ghost of Tsushima.
Robo getting jumped in Chrono Trigger was probably the first time a video game made me genuinely sad.