aspirin comes from plants breh
http://en.wikipedia.org/wiki/History_of_aspirin
The
history of aspirin (also known as
acetylsalicylic acid or
ASA) and the medical use of it and related substances stretches back to
antiquity, though pure ASA has only been manufactured and marketed since 1899. Medicines made from
willow and other
salicylate-rich plants appear in Egyptian pharonic pharmacology papyri
[1]from the second millennium BCE. Hippocrates referred to their use of salicylic tea to reduce fevers around 400 BCE[
citation needed], and were part of the pharmacopoeia of Western medicine in
Classical antiquity and the
Middle Ages. Willow bark extract became recognized for its specific effects on fever, pain and
inflammation in the mid-eighteenth century.
Lewis and Clark allegedly used willow bark tea in 1803-1806 as a remedy for fever for members of the famous expedition. By the nineteenth century pharmacists were experimenting with and prescribing a variety of chemicals related to
salicylic acid, the active component of willow extract.
In 1853, chemist
Charles Frédéric Gerhardt treated
acetyl chloride with
sodium salicylate to produce
acetylsalicylic acid for the first time;
[2] in the second half of the nineteenth century, other
academic chemists established the compound's chemical structure and devised more efficient methods of synthesis. In 1897, scientists at the drug and dye firm
Bayer began investigating acetylsalicylic acid as a less-irritating replacement for standard common salicylate medicines. By 1899, Bayer had dubbed this drug
Aspirin and was selling it around the world. The word
Aspirin was Bayer's brand name, rather than the generic name of the drug; however, Bayer's rights to the trademark were lost or sold in many countries.
[3] Aspirin's popularity grew over the first half of the twentieth century, spurred by its effectiveness in the wake of
Spanish flu pandemic of 1918, and aspirin's profitability led to fierce competition and the proliferation of aspirin brands and products. Some of the 1918 flu deaths were probably due to
Aspirin poisoning.
[4]