No, mathematics and numbers do not exist independently of humans. People used to believe that they did when Euclidean geometry was the only geometry known. "A triangle is 180 degrees anywhere in the universe regardless of whether humans exist or not" people thought; "Euclid's geometry is deductively true so it has to be objectively true" people argued. But then non-euclidean geometry came along as a result of mathematicians playing with axioms of Euclidean geometry. These types of geometries were also deductively true except that they made different predictions about abstract shapes and figures than Euclidean geometry. For example, under certain conditions it is possible to have a triangle that is more than 180 degrees. Shortest distance between two points on a curved surface is not a straight line.
So depending on axioms (fundamental assumptions) you can have different mathematical pictures of reality, meaning that math is a product of human interpretation of the world and not objective description of the world.