COVID-19 Pandemic (Coronavirus)

AquaCityBoy

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As expected unfortunately. This is an ongoing saga. We’re in the middle of a global fight.

2020: Episode I - The Phantom COVID Menace
:damn:

2021: Episode II - Attack of the Variants
:mjcry:

2022: Episode III - Revenge of the Sick
:deadrose:

2023: Episode IV - A New Hope
:blessed:

2024: Episode V - The Covid Strikes Back
:ufdup:.
 

☑︎#VoteDemocrat

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apnews.com
Top Chinese official admits vaccines have low effectiveness
By JOE McDONALD and HUIZHONG WU
6-7 minutes
BEIJING (AP) — China’s top disease control official, in a rare acknowledgement, said current vaccines offer low protection against the coronavirus and mixing them is among strategies being considered to boost their effectiveness.

China has distributed hundreds of millions of doses of domestically made vaccines abroad and is relying on them for its own mass immunization campaign.

But the director of the Chinese Center for Disease Control and Prevention, Gao Fu, said at a conference Saturday their efficacy rates needed improving.

“We will solve the issue that current vaccines don’t have very high protection rates,” Gao said in a presentation on Chinese COVID-19 vaccines and immunization strategies at a conference in the southwestern city of Chengdu. “It’s now under consideration whether we should use different vaccines from different technical lines for the immunization process.”

He also praised the benefits of mRNA vaccines, the technology behind the two vaccines seen as the most effective, Pfizer-BioNTech and Moderna, months after questioning whether the then-unproven method was safe.

In a message to The Associated Press, Gao said late Sunday night he was speaking about the effectiveness rates for “vaccines in the world, not particularly for China.” He did not respond to further questions about which vaccines he was referring to.

He directed the AP to an interview he did with the state-owned Global Times, which has published several articles raising doubts about the safety of Pfizer’s mRNA vaccine. Gao was quoted by the outlet Sunday as saying he was misunderstood and merely talking in general terms about improving vaccine efficacy.

Beijing earlier tried to promote doubt about the effectiveness of the Pfizer-BioNTech vaccine, which uses genetic code called messenger RNA, or mRNA, to prime the immune system.

Health officials at a news conference Sunday didn’t respond directly to questions about Gao’s comment or about possible changes in official plans. But another CDC official said Chinese developers are working on mRNA-based vaccines.

“The mRNA vaccines developed in our country have also entered the clinical trial stage,” said the official, Wang Huaqing. He gave no timeline for possible use.

Experts say mixing vaccines, or sequential immunization, might boost effectiveness. Researchers in Britain are studying a possible combination of Pfizer-BioNTech and the AstraZeneca vaccine.

Gao concluded his presentation Saturday with praise for mRNA vaccines and called for innovation in research.

“Everyone should consider the benefits mRNA vaccines can bring for humanity,” Gao said. “We must follow it carefully and not ignore it just because we already have several types of vaccines already.”

Gao previously questioned the safety of mRNA vaccines. He was quoted by the official Xinhua News Agency as saying in December he couldn’t rule out negative side effects because they were being used for the first time on healthy people, saying “there is a safety concern.”

Chinese state media and popular health and science blogs also questioned the safety and effectiveness of the Pfizer-BioNTech vaccine, though large-scale trials and the rollout of the vaccines in the U.S. have established its safety.

China currently has five vaccines in use in its mass immunization campaign, three inactivated-virus vaccines from Sinovac and Sinopharm, a one-shot vaccine from CanSino, and the last from Gao’s team in partnership with Anhui Zhifei Longcom.

The effectiveness of the vaccines range from just over 50% to 79%, based on what the companies have said.

The shot from Gao’s team, was given emergency use approval a month ago, and has not publicly disclosed data yet about its efficacy.

Pfizer and Moderna’s vaccines, which are primarily being used in developed countries, have both been shown to be about 95% in protecting against COVID-19 in studies.

As of April 2, some 34 million people in China have received the full two doses of Chinese vaccines and about 65 million received one, according to Gao.

Globally, public health experts have said that any vaccine that is 50% effective would be useful, and many governments have been eager to use Chinese vaccines as rich countries around the world have snapped up shots from Pfizer and Moderna.

WHO Director General Tedros Adhanom Ghebreysus said Friday that while one in four people in rich countries had received a vaccine, only one in 500 people in poorer countries had gotten a dose.

The coronavirus pandemic, which was first detected in central China in late 2019, marks the first time the Chinese drug industry has played a role in responding to a global health emergency.

Vaccines made by Sinovac, a private company, and Sinopharm, a state-owned firm, have made up the majority of Chinese vaccines distributed to several dozen countries including Mexico, Turkey, Indonesia, Hungary, Brazil and Turkey.

However, the companies have not publicly published peer-reviewed data on the final stage clinical trial research and been criticized for a lack of transparency.

Sinovac’s vaccine, for example, raised concerns when it was found to have different efficacy rates from each of the trials it conducted in different countries, ranging from around 50% to over 83%.

A Sinovac spokesman, Liu Peicheng, acknowledged varying levels of effectiveness have been found but said that can be due to the age of people in a study, the strain of virus and other factors.

Beijing has yet to approve any foreign vaccines for use in mainland China.

The Sinovac spokesman, Liu, said studies find protection “may be better” if time between vaccinations is longer than the current 14 days but gave no indication that might be made standard practice.

___

Wu reported from Taipei.

___

This story has been corrected to show that Chinese vaccines were donated or exported to several dozen countries, not 22, and that Sinovac is a private company, not state-owned.






ft.com
China considers mixing vaccines to bolster efficacy
Yuan Yang in Beijing and Primrose Riordan in Hong Kong April 11 2021
4-5 minutes
The Chinese Center for Disease Control and Prevention has raised the prospect of mixing vaccines and varying doses to boost efficacy, the first time a government body has acknowledged concerns over the effectiveness of homegrown jabs.

Gao Fu, CDC head, told a conference on Saturday that the agency was “considering how to solve the problem that the efficacy of existing vaccines is not high”, according to local media. Gao proposed mixing different vaccines as well as amending the sequence of doses, such as changing the number and quantity of doses, and the interval between them.

Any new strategy will have ramifications for the more than 20 countries that China said it was supplying in mostly bilateral “vaccine diplomacy” deals.

As of March, China had supplied 40m doses to countries across the globe, including Brazil, Serbia and the United Arab Emirates, prompting the US and its allies to launch their own drive to supply 1bn doses of Johnson & Johnson’s Covid-19 vaccine to south-east Asian nations.

Chile, which has relied on China’s Sinovac vaccine for its inoculation campaign, is in the midst of another Covid-19 wave from new variants. The country has administered 62 doses per 100 residents, according to the Financial Times vaccine tracker, the third-highest rate in the world.

A recent study of the effectiveness of Chile’s vaccination programme found the efficacy of a single dose of the Sinovac jab was just 3 per cent, compared with 56 per cent with two shots. However, local health experts have not linked the latest wave to the vaccine’s efficacy rate.

Social-media posts on Gao’s remarks were swiftly censored, according to Yanzhong Huang, a senior fellow for global health at the Council on Foreign Relations.

“It is the first time . . . a government official publicly admitted that the protection rate is a concern in the vaccination drive,” Huang added. China had administered 65m doses across the country by the middle of March.

Unlike other vaccine producers, China’s manufacturers have not published their phase 3 trial data, leading to accusations of a lack of transparency over the vaccine’s effectiveness on different groups.

For now, the main jabs approved for use in China are the traditional “inactivated virus” vaccines produced by Sinopharm, Sinovac and other domestic groups.

Sinopharm claims a 79 per cent efficacy rate, similar to those achieved by AstraZeneca in its US trials. However, while AstraZeneca revised down its rates after facing criticism for releasing incomplete data, neither Sinopharm nor any of its Chinese peers have released phase 3 data for public scrutiny.

Peter English, a retired communicable disease control consultant at Public Health England, said it was “astonishing” that phase 3 trial data for the Chinese vaccines had not yet been published.

“We have little information on how effective these vaccines are,” he said, adding efficacy data against variants of concern was needed. Still, English said it was “interesting” that China was considering mixing and matching vaccines after moves from France and Germany to do so following safety concerns about the Oxford/AstraZeneca shot.

Sinovac Biotech’s CoronaVac vaccine has an overall efficacy rate of 51 per cent among people aged between 18 and 60, according to documents published by a Hong Kong panel of experts.

However, CoronaVac phase 1 and 2 data published in The Lancet found the shots were “safe and well tolerated”.

Gao also warned that reopening China’s borders to foreigners, who have been barred from entering the country since March last year, posed a risk to elderly people, who have not yet been vaccinated.

The timing of relaxing border restrictions will affect attendees at Beijing’s Winter Olympic Games in February 2022.

Additional reporting by Donato Mancini in Rome
 

Theo Penn

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apnews.com
Top Chinese official admits vaccines have low effectiveness
By JOE McDONALD and HUIZHONG WU
6-7 minutes
BEIJING (AP) — China’s top disease control official, in a rare acknowledgement, said current vaccines offer low protection against the coronavirus and mixing them is among strategies being considered to boost their effectiveness.

China has distributed hundreds of millions of doses of domestically made vaccines abroad and is relying on them for its own mass immunization campaign.

But the director of the Chinese Center for Disease Control and Prevention, Gao Fu, said at a conference Saturday their efficacy rates needed improving.

“We will solve the issue that current vaccines don’t have very high protection rates,” Gao said in a presentation on Chinese COVID-19 vaccines and immunization strategies at a conference in the southwestern city of Chengdu. “It’s now under consideration whether we should use different vaccines from different technical lines for the immunization process.”

He also praised the benefits of mRNA vaccines, the technology behind the two vaccines seen as the most effective, Pfizer-BioNTech and Moderna, months after questioning whether the then-unproven method was safe.

The Chinese are outchea setting countries up with their bootleg knockoff vaccines while the WHO continue to lick their boots. Look at what’s happening to Chile as a result. They got over 70% of their population vaccinated with that Chinese garbage and are currently getting destroyed by COVID anyway.
 

Asicz

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The vaccines work.

If in his part of India the population vaccinated quickly enough, herd immunity would have been achieved and the likelihood of him and his fam getting infected would have been slim.

The vaccines protect against severe disease and and have like 95% efficacy in trials. And near 100% efficacy for protecting against death.
 
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Asicz

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I hate that potentially vaccine hesitant and resistant people will use a extremely rare case where a previously immnunocomprimised vaccinated indiviual dies. Its not the norm.

And the best way to protect against it is herd immunity through vaccination and other public health messures.
 
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The vaccines work.

If in his oart of India the population csccinated quickly enough herd immunity woyld have been achieved and yhe likilyhood og him and his fam getting infected would have been slim.

The vaccines protect against severe disease and and have like 95% efficacy in trials. And near 100% efficacy for protecting against death.

BBV152 - Wikipedia
 
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