The researchers also used a novel approach to deliver the drug, called a microneedle array, to increase potency. This array is a fingertip-sized patch of 400 tiny needles that delivers the spike protein pieces into the skin, where the immune reaction is strongest. The patch goes on like a Band-Aid and then the needles—which are made entirely of sugar and the protein pieces—simply dissolve into the skin.
“We developed this to build on [URL='https://www.pittmed.health.pitt.edu/story/sticking-it-disease']the original scratch method used to deliver the smallpox vaccine
to the skin, but as a high-tech version that is more efficient and reproducible patient to patient,” Falo said. “And it’s actually pretty painless—it feels kind of like Velcro.”
The system is also highly scalable. The protein pieces are manufactured by a “cell factory”—layers upon layers of cultured cells engineered to express the SARS-CoV-2 spike protein—that can be stacked further to multiply yield. Purifying the protein can also be done at industrial scale. Mass-producing the microneedle array involves spinning down the protein-sugar mixture into a mold using a centrifuge. Once manufactured, the vaccine can sit at room temperature until it’s needed, eliminating the need for refrigeration during transport or storage.
NBA got better tech than the president
That whole presser is straight@ Trump telling a reporter "You'll never make it". Reporter had a legit question but of course Trump had to make it about himself.
How’s that happen when your on lockdown
During the 2018-2019 season, the CDC estimates 16.5 million people went to a health care provider for the flu and more than 34,000 people died in the U.S. The prior season saw 61,000 deaths.
United States
Coronavirus Cases:
366,906
Deaths:
10,868
200 to 215 people are dying everyday in NY at home?
Guys..... do you get that impression from the news?
If you watch the news does it feel like that many are dying everyday?
At least saved more sports attendees and players than anyone else. nikkas did NOT have problems going to those games up until thatI was thinking about something the other day:
Shutting down the NBA was the first "domino" that led to all major corporations starting to shut down the next day.
Its possible that Adam Silver actually saved more lives in the US with that than any other single person during this crisis.