I think DC villains are hella weak. The only one's with some merit will be Darkseid, Black Atom, Zod and Sinestro. No reality warpers and no Infinity Gauntlet, so just pure power and wits. Batman's rogue gallery goes early, so does Kingpin, Doomsday will be out of there, most of Spider-Man's rogue gallery, Lex gets offed.
We got heavy hitters and heavy hitters with intelligence. First, it comes down to who Apocalypse is able to make a Horseman. That will tip the scales in his favor. Hmmm, I actually think Apocalypse will sit atop of the throne when all said and done...his ability is basically Darwinism...even though he hasn't been powerful in decades.