stay away from rookie RBs. Only Rookie RB i would take a chance on is Melvin Gordon, and if you can get Todd Gurley in the mid-late rounds, i would snag him up.
I like:
WR Martavis Bryant
RB Jeremy Hill
WR John Brown (if Palmer can stay healthy, he's gonna ball out)
TE Austin Seferain-Jenkins
RB Carlos Hyde (although the O-Line isn't great right now, but i think having Kaep back there helps him)
WR Odell Beckham Jr.
WR Mike Evans
WR Brandon Cooks
WR Jordan Matthews
WR Jarvis Landry
Those guys I feel that will make an immediate impact from week 1 and so on.
RB Kelvin Benjamin can be inefficient at times, but him and Cam gotta build a rapport if they both want to succeed.
RB TJ Yeldon is another good rookie RB, but that all depends on the Jags offense. He's definitely the main guy in the backfield for that team. Blake Bortles gotta step it up this year.
I like RB Ameer Abdullah in PPR Leagues, but probably wont score a lot of TDs because Joique will be the primary goal line ball carrier.
WR Breshad Perriman is raw but has great upside. He's been looking good during camp. Trestman being there will help as well Joe Flacco's huge arm to throw him the ball down the field
WR Kevin White should be a good compliment to Alshon Jeffries and Jay Cutler is a gunslinger so he'll get some balls thrown to him.