Musk claims no monkeys died from Neuralink implants. His own scientists' lab notes tell the opposite story.

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Dangers of neural implants aside, the audacity of his lies and lack of ethics are wild. He has zero empathy, zero human humility. I wouldn't be the slightest bit surprised to discover that he's a literal psychopath or sociopath.


Musk first acknowledged the deaths of the macaques on September 10 in a reply to a user on his social networking app X (formerly Twitter). He denied that any of the deaths were “a result of a Neuralink implant” and said the researchers had taken care to select subjects who were already “close to death.” Relatedly, in a presentation last fall Musk claimed that Neuralink’s animal testing was never “exploratory,” but was instead conducted to confirm fully formed scientific hypotheses. “We are extremely careful,” he said.


Reality:

Public records reviewed by WIRED, and interviews conducted with a former Neuralink employee and a current researcher at the University of California, Davis primate center, paint a wholly different picture of Neuralink’s animal research. The documents include veterinary records, first made public last year, that contain gruesome portrayals of suffering reportedly endured by as many as a dozen of Neuralink’s primate subjects, all of whom needed to be euthanized. These records could serve as the basis for any potential SEC probe into Musk’s comments about Neuralink, which has faced multiple federal investigations as the company moves toward its goal of releasing the first commercially available brain-computer interface for humans.



For example, in an experimental surgery that took place in December 2019, performed to determine the “survivability” of an implant, an internal part of the device “broke off” while being implanted. Overnight, researchers observed the monkey, identified only as “Animal 20” by UC Davis, scratching at the surgical site, which emitted a bloody discharge, and yanking on a connector that eventually dislodged part of the device. A surgery to repair the issue was carried out the following day, yet fungal and bacterial infections took root. Vet records note that neither infection was likely to be cleared, in part because the implant was covering the infected area. The monkey was euthanized on January 6, 2020.



Additional veterinary reports show the condition of a female monkey called “Animal 15” during the months leading up to her death in March 2019. Days after her implant surgery, she began to press her head against the floor for no apparent reason; a symptom of pain or infection, the records say. Staff observed that though she was uncomfortable, picking and pulling at her implant until it bled, she would often lie at the foot of her cage and spend time holding hands with her roommate.

Animal 15 began to lose coordination, and staff observed that she would shake uncontrollably when she saw lab workers. Her condition deteriorated for months until the staff finally euthanized her. A necropsy report indicates that she had bleeding in her brain and that the Neuralink implants left parts of her cerebral cortex “focally tattered.”




Yet another monkey, Animal 22, was euthanized in March 2020 after his cranial implant became loose. A necropsy report revealed that two of the screws securing the implant to the skull loosened to the extent that they “could easily be lifted out.” The necropsy for Animal 22 clearly states that “the failure of this implant can be considered purely mechanical and not exacerbated by infection.” If true, this would appear to directly contradict Musk’s statement that no monkeys died as a result of Neuralink’s chips.



Shown a copy of Musk’s remarks on X about Neuralink’s animal subjects being “close to death already,” a former Neuralink employee alleges to WIRED that the claim is “ridiculous,” if not a “straight fabrication.” “We had these monkeys for a year or so before any surgery was performed,” they say. The ex-employee, who requested anonymity for fear of retaliation, says that up to a year’s worth of behavioral training was necessary for the program, a time frame that would exempt subjects already close to death.

A doctoral candidate currently conducting research at the CNPRC, granted anonymity due to a fear of professional retaliation, likewise questions Musk’s claim regarding the baseline health of Neutralink’s monkeys. “These are pretty young monkeys,” they tell WIRED. “It’s hard to imagine these monkeys, who were not adults, were terminal for some reason.”
 

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85% of Neuralink implant wires are already detached, says patient​

In an interview, Noland Arbaugh says the company wanted to avoid further surgery.

Andrew Paul

Posted On May 21, 2024 12:25 PM EDT

Hand holding Neuralink implant

The first human recipient says the device is performing better than before following algorithm changes. Neuralink

An estimated 85-percent of Neuralink’s brain-computer interface (BCI) implant threads connected to the first human patient’s motor cortex are now completely detached and his brain has shifted inside his skull up to three times what the company expected, volunteer Noland Arbaugh told The Wall Street Journal on Monday. Arbaugh also stated Neuralink has since remedied the initial performance issues using an over-the-air software update and is performing better than before, but the latest details continue to highlight concerns surrounding the company’s controversial, repeatedly delayed human implant study.

Neuralink’s coin-sized N1 BCI implant’s 64 wires thinner than a human hair are inserted a few millimeters into the motor cortex. Each thread contains 16 electrodes that translate a user’s neural activity into computer commands like typing and cursor movement. Around 870 of the 1024 electrodes in Arbaugh’s implant are no longer functional—an issue that allegedly took Neuralink a “few weeks” to remedy, reports The WSJ. When Arbaugh asked if his implant could be removed, fixed, or even replaced, Neuralink’s medical team relayed they would prefer to avoid another brain surgery and instead gather more information.

[Related: Every human testicle contained microplastics in a new study]

In an update quietly published earlier this month, the company says it ultimately determined that the malfunction had reduced the implant’s bits-per-second (BPS) rate, a measure of the BCI’s performance speed and accuracy. A modification to “the recording algorithm” allowed Arbaugh’s device to become “more sensitive to neural population signals, improved the techniques to translate these signals into cursor movements, and enhanced the user interface.”

“These refinements produced a rapid and sustained improvement in BPS, that has now superseded Noland’s initial performance,” Neuralink wrote next to a data graph illustration with no additional citation. As The Register explains, this potentially now “[leaves] just nine or ten of the original 64” threads in working condition. Arbaugh’s post-surgery side-effects support previous reports that Neuralink engineers have known for years about the implant’s potential to move within a subject’s skull.

An estimated 1,000 people have purportedly submitted applications to participate in Neuralink’s ongoing PRIME Study, but less than a tenth of them are qualified for the trial. The company has previously stated it hopes to perform an additional nine implant surgeries by the end of the year, and aims to complete its second procedure in June. Documents reviewed by The WSJ indicate Neuralink believes a potential remedy to the ongoing wire retraction issue may come from implanting the threads deeper into the brain.

“We’re still in the early stages of the PRIME Study and plan to provide additional updates as we continue to work with our first participant, as well as other participants in the future,” Neuralink wrote in an update earlier this year. Below each blog post is the stipulation, “We do not guarantee any benefit by participating in the PRIME Study.”
 

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Documents reviewed by The WSJ indicate Neuralink believes a potential remedy to the ongoing wire retraction issue may come from implanting the threads deeper into the brain.


:mjlol:



They better be required to complete each trial through to proven implant stability for years before they can expand the trial. If they're scared to go back in for additional brain surgeries, then if they have a funky result late in the line, everyone who has just started gonna get screwed. This isn't like a medication you can stop taking or a vaccine that flushes from your system, this is a foreign body that they want to implant "deeper" into your brain.
 

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Yo they covered-up health issues in their pig trials too. :heh:





In 2022, the FDA initially rejected Neuralink’s application to begin human trials, and raised safety concerns about the threads, Reuters exclusively reported last year.

Neuralink conducted additional animal testing to address those concerns, and the FDA last year granted the company approval to begin human testing.

The company found that a subset of pigs implanted with its device developed a type of inflammation in the brain called granulomas, raising concerns among Neuralink’s researchers that the threads could be the cause, according to three sources familiar with the matter and records seen by Reuters. Granulomas are an inflammatory tissue response that can form around a foreign object or an infection.

In at least one case, a pig developed a severe case of the condition. Company records reviewed by Reuters show that the pig developed a fever and was heaving after surgery. Neuralink’s researchers did not recognize the extent of the problem until examining the pig’s brain post-mortem.

Inside Neuralink, researchers debated how to rectify the issue and commenced a months-long investigation, said the sources familiar with the events.

Ultimately, the company could not determine the cause of the granulomas, but concluded that the device and the attached threads were not to blame, one of the sources said.




In 2021, Neuralink implanted 25 out of 60 pigs with devices that were the wrong size. Afterward, the company killed all the affected pigs. Staff told Reuters that the mistake could have been averted if they’d had more time to prepare.





Think of all the random problems and recalls that Teslas have, and then imagine letting the person responsible for that poor oversight put something into your brain. :mjlol:
 

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This isn't even my #1 or #2 biggest concern about these interfaces, and it still looks fukking terrible. It seems like the FDA is only granting him approval to put these things in the brains of quadriplegics and he's using that as a workaround to test technology he wants for completely different purposes. Unethical and dangerous as hell.


This article discusses a number of the issues I have with the technology (not all of them) as well as pointing out numerous times the company has chosen speed over safety and even purposely made decisions that were not in line with the welfare of the patient.


 

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THE TAN MACAQUE with the hairless pink face could do little more than sit and shiver as her brain began to swell. The California National Primate Center staff observing her via livestream knew the signs. Whatever had been done had left her with a “severe neurological defect,” and it was time to put the monkey to sleep. But the client protested; the Neuralink scientist whose experiment left the 7-year-old monkey’s brain mutilated wanted to wait another day. And so they did.

As the attending staff sat back and observed, the monkey seized and vomited. Her pupils reacted less and less to the light. Her right leg went limp, and she could no longer support the weight of her 15-pound body without gripping the bars of her cage. One attendant moved a heat lamp beside her to try to stop her shaking. Sometimes she would wake and scratch at her throat, retching and gasping for air, before collapsing again, exhausted.

An autopsy would later reveal that the mounting pressure inside her skull had deformed and ruptured her brain. A toxic adhesive around the Neuralink implant bolted to her skull had leaked internally. The resulting inflammation had caused painful pressure on a part of the brain producing cerebrospinal fluid, the slick, translucent substance in which the brain sits normally buoyant. The hind quarter of her brain visibly poked out of the base of her skull.

On September 13, 2018, she was euthanized, records obtained by WIRED show. This episode, regulators later acknowledged, was a violation of the US Animal Welfare Act; a federal law meant to set minimally acceptable standards for the handling, housing, and feeding of research animals. There would be no consequences, however. Between 2016 and 2021, the United States Department of Agriculture (USDA) enforced the humane treatment of animals through what it called “teachable moments.” Because the center—home to a colony of nearly 5,000 primates run by the University of California–Davis—had proactively reported the violation, it could not be legally cited.

And neither could Neuralink. “If you want to split hairs,” a former employee tells WIRED, “the implant itself did not cause death. We sacrificed her to end her suffering.” The employee, who signed a confidentiality agreement, asked not to be identified.





The article goes on to detail how Neuralink has gone to lengths to prevent the release of any photos or video of their dying monkeys.
 
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