TL;DR
Bradley Cooper stars as a womanzing playboy who has literally banged every hot chick in NYC... but he's in a cold streak. He treats woman like shyt and has turned to retreads. We meet one, she tells him to "go fukk himself." You with me so far?
Bradley Cooper shares a deluxe apartment with his best friend played by Jesse Eisenberg, a sheepish guy who is controlled by his total c*nt of a girlfriend played by flavor the week, new version of Sarah Silverman.
Bradley Cooper lives next door to a struggling antisocial scientist who never leaves his apartment but constantly makes a racket working day and night on his new project (a machine that records dreams or some shyt.) Finally one day BC has enough. He barges in and finds this weird dude working on a giant portal like device. BC agrees to be a test subject as there is one girl who he just cant land, and he likes the idea of watching a porno of himself fukking her.
BC steps in and WOOSH, a light engulfs him... he's gone. LATER - BC exits the machine, discombobulated he stumbles on the wires and the machine shorts out. He runs out before the scientist can hassle him.
BC goes home, and finds some big dude sitting on his couch. He panics, the big guy threatens to kick his ass, so like the bytch he is (you see BC talks a big game, but he really hates himself deep down) he runs out of the building... something's not right. The fukk? what is all this? "Aunt Josephenes? Why that bar was called "Uncle Joe's just yesterday."
BC has been transported to a universe where everything is the same... except everyone is of the opposite sex! WHATTTTTT?!
BC dreamt of a world of women he hasn't fukked and well I'll be a son of a bytch, he was somehow transported there, but he's still punchdrunk from the interdimensional travel, nothing is really registering. He wanders the streets and everything is opposite (bit characters and locations already established early in act 1)
He runs home to find the big guy talking down to a mousy little cute chick... he asks them whats going in, why are you in my house? Blah blah, mousy says Eisenberg's famous catchphrase (established early in act 1) BC freaks. How could this be? He learns that they had a female roommate, but she finally moved out bc the guy was too abusive.
BC shakes it off and decides this universe is his playground. He first has a innter monologue wondering if it would be gay to have sex with women he knew as men... but BC don't care, he's off to get his dikk wet. This is the "fun and games" segment, where he fukks chicks he kinda knows and the awkwardness of the audience's knowledge that he knows them as men drives the comedy. He meets the retread from eariler as a guy, and he punches him in the face.
Mid 2nd act - something happens, BC is out of money and he doesn't know what to do. He, as a male, does not exist in this universe. He cant go to work, he has no identity, so he runs back to the scientists apartment. She opens the door, looks exactly the same only female. They have a Marty/Doc Brown like discovery discussion. She tells him that BC fukked the machine up and its going to take some time. Lay low, he can stay there, blah blah.
From this point on the movie is about self discovery. BC realizes the err of his ways through interactions with opposite-characters he already knows. He sticks up for his best friend (gets into a brawl with the abusive boyfriend), he gets the scientist to lighten up. Then at the end of act 2, all hell breaks loose, when BC returns "home" and finds... himself!!!!
Scientist warns him that contact with his female counterpart can fukk up the time/space continuum... but BC has so many questions. Scientist tells him to stay clear... but you know BC ain't gonna do that. He wants to know what life is like from the other side. Female BC is an absolute slut. She takes dikk daily, and acts like a total stuck up bytch. This hits BC like a ton of bricks "is that what I'm like?" ...but ya know what... she's fukkin hot.
The climax results in Scientist fixing the machine, and running to stop BC, who is about to have sex with the female version of himself. Ya see, this would cause two worlds to somehow collapse in on themselves. This can't happen.
This summer, Bradley Cooper stars in "Go F*** Yourself."
Last 10 - BC returns home. Was it all a dream? Nope, there is something to remind him of the weird journey he'd just been on. BC tells the Scientist about it, changes his life for the better. He convinces Eisenberg to ditch the bytch, and he makes a vow that he's ready to settle down and find the girl of his dreams. We get a funny little bit of he and Jesse sitting in Uncle Joe's. BC is very uncomfortable around his male friends bc he fukked them in the other world. We end on a sweet, shy beauty sitting in the corner. BC approaches her and instead of his usual cheesy line, he starts a real conversation with her.
That's a hit, you know it's a hit.
(this was based on a joke idea, and I just now really fleshed that out... I need a better hobby)