One thing I gotta say tho is I don’t recall Pac saying that Stretch n nem set him up. He was moreso pissed that he didn’t show the same heart that Pac did in that moment + he got chummy with Big n nem which he took as a betrayal.
As far as that goes, personally I think it’s a similar case to Big in that they actually from NYC and their loved ones could get touched by Henchmen n nem. I totally get where Pac coming from but it’s human nature to practice self preservation.