Yeah and No.
No and I only say that because alive or dead, his mentality will remain the same. He nor anyone in his crew will actually look at the physical things they're doing to their bodies with objectivity.
If he dies, YMCMB is just gonna smoke a bunch of Ls and pop pills for him. Nobody is gonna change their life or their lifestyle. Nobody is gonna use this as an opportunity to stop or at least modify the drug culture in hip hop. Even if Wayne dies, there will not be one person in that org that will stop folks from using that around them. They'll just continue with the same "If that's what you wanna do, I can't stop you" mentality most of our civilization has.
The net affect of him living or dieing = 0 when it comes to what's really important.
His life, his fame, everything he's gained is because of drugs. Whether it be pushing it or using it and making music. What is he without the pills? What is he without that lifestyle? That's his celebrity status. We bump his music because that's what we identify with. He can't be a rapper without the drugs, p*ssy and gang affiliation.
And we know he'll never give any of those things up. And we know he doesn't want to either.