The Interstate 5 Bridge over the Skagit River in Washington state collapsed around 7 p.m. on Thursday, dumping cars and people into the water, KIRO-TV reported.
According to the Trooper Mark Francis, public information officer for the Washington State Patrol, both north and southbound lanes of the interstate were affected.
Rescue teams are currently searching the river for survivors. Several people have been spotted sitting on their cars in the water, waiting for help. First responders have already pulled one man off the roof of his vehicle, prompting nearby eyewitnesses to applaud, The Skagit Valley Herald reported.
There was no immediate word on injuries. Cause of the collapse is unknown at this time.
Drivers are being advised to avoid the area. The freeway has also been closed, Northwest Cable News reported.
The 1,111-ft. Skagit River Bridge is located between Burlington and Mt. Vernon, about 60 miles north of Seattle. Built in 1955, BridgeHunter.com notes that the four-lane structure sees an average daily traffic of about 71,000.
One in nine of the nation's bridges has been rated as structurally deficient, the American Society of Civil Engineers 2013 Report Card for America's Infrastructure reported. The Federal Highway Administration estimates that it would cost $20.5 billion a year to eliminate the country's bridge deficient backlog by 2028.